U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

col28a2b collagen, type XXVIII, alpha 2b [ Danio rerio (zebrafish) ]

Gene ID: 100002791, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
col28a2bprovided by ZNC
Official Full Name
collagen, type XXVIII, alpha 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-762
See related
Ensembl:ENSDARG00000100781 AllianceGenome:ZFIN:ZDB-GENE-130530-762
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
col28a1b; col28a1l; zmp:0000000759
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within cell adhesion. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Is expressed in integument; intestine; liver; and thymus. Orthologous to human COL28A1 (collagen type XXVIII alpha 1 chain). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See col28a2b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (3636420..3675319)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (3420073..3513215)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene fatty acid amide hydrolase Neighboring gene diencephalon/mesencephalon homeobox 1b Neighboring gene kelch-like family member 41b Neighboring gene peptidylprolyl isomerase G (cyclophilin G)

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structure, evolution and expression of collagen XXVIII: Lessons from the zebrafish. Gebauer JM, et al. Matrix Biol, 2016 Jan. PMID 26235539
  2. Fishing for collagen function: About development, regeneration and disease. Bretaud S, et al. Semin Cell Dev Biol, 2019 May. PMID 30312775
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
collagen alpha-1(XXVIII) chain
Names
collagen type XXVIII alpha 1 b
collagen, type XXVIII, alpha 1 like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    3636420..3675319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476979.2 → XP_021332654.1  collagen alpha-1(XXVIII) chain

    UniProtKB/TrEMBL
    A0A8M9Q6B7
    Related
    ENSDARP00000141077.2, ENSDART00000172078.2
    Conserved Domains (5) summary
    pfam01391
    Location:503 → 562
    Collagen; Collagen triple helix repeat (20 copies)
    PHA03169
    Location:261 → 444
    PHA03169; hypothetical protein; Provisional
    cd01450
    Location:65 → 228
    vWFA_subfamily_ECM; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam00014
    Location:1147 → 1193
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    cl00057
    Location:814 → 1006
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials