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cnot2 CCR4-NOT transcription complex, subunit 2 [ Danio rerio (zebrafish) ]

Gene ID: 100037372, updated on 4-Jan-2025

Summary

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Official Symbol
cnot2provided by ZNC
Official Full Name
CCR4-NOT transcription complex, subunit 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-70
See related
Ensembl:ENSDARG00000061802 AllianceGenome:ZFIN:ZDB-GENE-070410-70
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:162316
Summary
Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be part of CCR4-NOT core complex. Is expressed in telencephalon. Orthologous to human CNOT2 (CCR4-NOT transcription complex subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See cnot2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (28678888..28713510)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (28235694..28271213)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene formin binding protein 4 Neighboring gene leucine rich repeat containing 10 Neighboring gene WASH complex subunit 4 Neighboring gene solute carrier family 41 member 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Wang D, et al. Proc Natl Acad Sci U S A, 2007 Jul 24. PMID 17640903, Free PMC Article
  2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CCR4-NOT core complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CCR4-NOT transcription complex subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089524.1 → NP_001082993.1  CCR4-NOT transcription complex subunit 2

    See identical proteins and their annotated locations for NP_001082993.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134959
    UniProtKB/TrEMBL
    A0A8M2BA58, A4QN63
    Related
    ENSDARP00000082816.5, ENSDART00000088383.7
    Conserved Domains (1) summary
    pfam04153
    Location:376 → 499
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    28678888..28713510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163111.5 → XP_005163168.1  CCR4-NOT transcription complex subunit 2 isoform X2

    See identical proteins and their annotated locations for XP_005163168.1

    UniProtKB/TrEMBL
    A0A8M2BA58, A4QN63
    Conserved Domains (1) summary
    pfam04153
    Location:376 → 499
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

  2. XM_005163109.5 → XP_005163166.1  CCR4-NOT transcription complex subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BA34
    Conserved Domains (1) summary
    pfam04153
    Location:386 → 509
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

  3. XM_005163110.5 → XP_005163167.1  CCR4-NOT transcription complex subunit 2 isoform X2

    See identical proteins and their annotated locations for XP_005163167.1

    UniProtKB/TrEMBL
    A0A8M2BA58, A4QN63
    Conserved Domains (1) summary
    pfam04153
    Location:376 → 499
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

  4. XM_068217296.1 → XP_068073397.1  CCR4-NOT transcription complex subunit 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BA58, A4QN63
Nucleotide Protein
Heading Accession and Version

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