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Ramacl RNA guanine-7 methyltransferase activating subunit like [ Mus musculus (house mouse) ]

Gene ID: 100038538, updated on 27-Nov-2024

Summary

Official Symbol
Ramaclprovided by MGI
Official Full Name
RNA guanine-7 methyltransferase activating subunit likeprovided by MGI
Primary source
MGI:MGI:3642136
See related
Ensembl:ENSMUSG00000074826 AllianceGenome:MGI:3642136
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10767
Summary
Predicted to enable RNA binding activity and enzyme activator activity. Predicted to be located in nucleus. Predicted to be part of mRNA cap methyltransferase RNMT:RAMAC complex and mRNA capping enzyme complex. Orthologous to human RAMAC (RNA guanine-7 methyltransferase activating subunit) and RAMACL (RNA guanine-7 methyltransferase activating subunit like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E18 (RPKM 3.3), CNS E14 (RPKM 2.9) and 26 other tissues See more
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Genomic context

See Ramacl in Genome Data Viewer
Location:
13 B3; 13 34.54 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67053479..67057230)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (66905415..66909166)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34888 Neighboring gene high mobility group box 2 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67006259-67006368 Neighboring gene ubiquinol-cytochrome c reductase binding protein Neighboring gene mitochondrial transcription termination factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10799 Neighboring gene STARR-seq mESC enhancer starr_34889 Neighboring gene phosphatidylserine synthase 1 Neighboring gene RIKEN cDNA 4933433G19 gene Neighboring gene STARR-seq mESC enhancer starr_34892 Neighboring gene zinc finger protein 712 Neighboring gene STARR-positive B cell enhancer ABC_E3085

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme activator activity ISO
Inferred from Sequence Orthology
more info
 
enables molecular function activator activity ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
part_of mRNA cap methyltransferase RNMT:RAMAC complex ISO
Inferred from Sequence Orthology
more info
 
part_of mRNA capping enzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mRNA capping enzyme complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RNA guanine-N7 methyltransferase activating subunit-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177750.1NP_001171221.1  RNA guanine-N7 methyltransferase activating subunit-like

    See identical proteins and their annotated locations for NP_001171221.1

    Status: VALIDATED

    Source sequence(s)
    AC124433
    Consensus CDS
    CCDS56889.1
    UniProtKB/TrEMBL
    Q3TQP0
    Related
    ENSMUSP00000133648.2, ENSMUST00000099412.3
    Conserved Domains (1) summary
    pfam15320
    Location:1084
    RAM; mRNA cap methylation, RNMT-activating mini protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    67053479..67057230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)