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Dynlt2a3 dynein light chain Tctex-type 2A3 [ Mus musculus (house mouse) ]

Gene ID: 100041586, updated on 27-Nov-2024

Summary

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Official Symbol
Dynlt2a3provided by MGI
Official Full Name
dynein light chain Tctex-type 2A3provided by MGI
Primary source
MGI:MGI:3781595
See related
Ensembl:ENSMUSG00000116780 AllianceGenome:MGI:3781595
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LC2; Tcte3; Gm3417; Tcte-3; Tctex2; Tctex4; Dynlt2c; TCTEX-2; TCTEX-4; Tctex1d3
Summary
This gene is one of three genes with a very high degree of similarity to each other within a 77 kb genomic span on Chromosome 17 A2. This gene is the most proximal copy of the three genes. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis adult (RPKM 444.7) See more
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Genomic context

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See Dynlt2a3 in Genome Data Viewer
Location:
17 A2; 17 8.95 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15184451..15199074, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (14964189..14978812, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_41895 Neighboring gene WD repeat domain 27 Neighboring gene predicted gene, 23352 Neighboring gene STARR-seq mESC enhancer starr_41897 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:15046536-15046719 Neighboring gene RIKEN cDNA 1600012H06 gene Neighboring gene STARR-positive B cell enhancer ABC_E9166 Neighboring gene PHD finger protein 10 Neighboring gene STARR-seq mESC enhancer starr_41898 Neighboring gene ER membrane associated RNA degradation like 2 Neighboring gene predicted gene 3255 Neighboring gene dynein light chain Tctex-type 2A2 Neighboring gene ER membrane associated RNA degradation like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tctex2: a sperm tail surface protein mapping to the t-complex. Huw LY, et al. Dev Biol, 1995 Jul. PMID 7601308
  2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
t-complex-associated testis expressed 3-like
Names
T-complex testis-specific protein 2
T-complex testis-specific protein 3
T-complex-associated testis-expressed protein 3
T-complex-associated testis-expressed protein 4
Tctex1 domain-containing protein 3
dynein light chain Tctex-type 2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123368.1 → NP_001116840.1  t-complex-associated testis expressed 3-like isoform 1

    See identical proteins and their annotated locations for NP_001116840.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC182749
    Consensus CDS
    CCDS49959.1
    UniProtKB/Swiss-Prot
    P11985, P51806, Q66L72, Q7TN76, Q9D9X4
    Related
    ENSMUSP00000095011.5, ENSMUST00000097399.6
    Conserved Domains (1) summary
    pfam03645
    Location:94 → 189
    Tctex-1; Tctex-1 family

  2. NM_001360661.1 → NP_001347590.1  t-complex-associated testis expressed 3-like isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2 which is shorter, compared to isoform 1.
    Source sequence(s)
    AC182749
    Consensus CDS
    CCDS88996.1
    Related
    ENSMUSP00000155901.2, ENSMUST00000231584.2
    Conserved Domains (1) summary
    pfam03645
    Location:37 → 137
    Tctex-1; Tctex-1 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    15184451..15199074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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