Gsta13 glutathione S-transferase alpha 13 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gsta13provided by MGI
Official Full Name: glutathione S-transferase alpha 13provided by MGI
Primary source: MGI:MGI:3826440
See related: Ensembl:ENSMUSG00000111709 AllianceGenome:MGI:3826440
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Timd5; Gm3776
Summary: Predicted to enable several functions, including anion binding activity; dinitrosyl-iron complex binding activity; and glutathione peroxidase activity. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; heart; skeleton; and urinary system. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in stomach adult (RPKM 82.8), duodenum adult (RPKM 74.7) and 3 other tissues See more
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Genomic context

Location:: 9 E1; 9 43.65 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (78164411..78176448)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (78257129..78269166)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables dinitrosyl-iron complex binding	ISO Inferred from Sequence Orthology more info
enables fatty acid binding	ISO Inferred from Sequence Orthology more info
enables glutathione binding	ISO Inferred from Sequence Orthology more info
enables glutathione peroxidase activity	ISO Inferred from Sequence Orthology more info
enables glutathione transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione transferase activity	ISO Inferred from Sequence Orthology more info
enables molecular_function	ND No biological Data available more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables steroid delta-isomerase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in glutathione metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in xenobiotic metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: Glutathione S-transferase A1

Names: glutathione S-transferase, alpha 2 family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243092.1 → NP_001230021.1 Glutathione S-transferase A1

See identical proteins and their annotated locations for NP_001230021.1

Status: VALIDATED

Source sequence(s)

AC159313

Consensus CDS

CCDS90631.1

UniProtKB/TrEMBL

Q6P8Q0, Q8K0V9

Related

ENSMUSP00000150224.2, ENSMUST00000217203.2

Conserved Domains (3) summary

PTZ00057
Location:1 → 198

PTZ00057; glutathione s-transferase; Provisional

cd03208
Location:86 → 220

GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases

cd03077
Location:4 → 82

GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...