Alyreffm8 Aly/REF export factor family member 8 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Alyreffm8provided by MGI
Official Full Name: Aly/REF export factor family member 8provided by MGI
Primary source: MGI:MGI:3782487
See related: Ensembl:ENSMUSG00000096744 AllianceGenome:MGI:3782487
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm4307
Summary: Predicted to enable C5-methylcytidine-containing RNA reader activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm and nucleus. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to colocalize with chromosome, telomeric region. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 10 D1; 10 51.46 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (100197200..100198109)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (100361338..100362247)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables C5-methylcytidine-containing RNA reader activity	ISO Inferred from Sequence Orthology more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in RNA export from nucleus	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in mRNA export from nucleus	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	ISO Inferred from Sequence Orthology more info
is_active_in cellular_component	ND No biological Data available more info
colocalizes_with chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
part_of exon-exon junction complex	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of transcription export complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: uncharacterized protein LOC100043239

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166641.1 → NP_001160113.1 uncharacterized protein LOC100043239

See identical proteins and their annotated locations for NP_001160113.1

Status: VALIDATED

Source sequence(s)

AC164629

Consensus CDS

CCDS48683.1

UniProtKB/TrEMBL

B2RY44, E9PZY4

Related

ENSMUSP00000135905.3, ENSMUST00000177945.2

Conserved Domains (3) summary

COG0724
Location:79 → 163

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12680
Location:86 → 160

RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins

pfam07078
Location:6 → 59

FYTT; Forty-two-three protein