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slc6a11b solute carrier family 6 member 11b [ Danio rerio (zebrafish) ]

Gene ID: 100150472, updated on 4-Jan-2025

Summary

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Official Symbol
slc6a11bprovided by ZNC
Official Full Name
solute carrier family 6 member 11bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-121116-2
See related
Ensembl:ENSDARG00000087981 AllianceGenome:ZFIN:ZDB-GENE-121116-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
slc6a11
Summary
Predicted to enable symporter activity. Predicted to be located in membrane. Is expressed in brain. Orthologous to human SLC6A11 (solute carrier family 6 member 11). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See slc6a11b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (1090701..1134793, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (1068449..1108224, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 1b Neighboring gene uncharacterized LOC100003140 Neighboring gene uncharacterized LOC137496749 Neighboring gene ATPase plasma membrane Ca2+ transporting 2 Neighboring gene isoleucyl-tRNA synthetase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Swaminathan A, et al. Curr Biol, 2018 Jun 18. PMID 29861134
  2. Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits. Chen J, et al. Nat Neurosci, 2020 Oct. PMID 32895565, Free PMC Article
  3. Environmental concentration of fluoxetine disturbs larvae behavior and increases the defense response at molecular level in zebrafish (Danio rerio). Parolini M, et al. Environ Sci Pollut Res Int, 2019 Dec. PMID 31659707
  4. γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment. Samarut É, et al. Epilepsia, 2018 Nov. PMID 30324621
  5. TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Yang RM, et al. Cell Death Differ, 2019 Nov. PMID 30824836, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sodium- and chloride-dependent GABA transporter 3; solute carrier family 6 member 11b
Names
solute carrier family 6 (neurotransmitter transporter), member 11
solute carrier family 6 (neurotransmitter transporter), member 11b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    1090701..1134793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017358255.3 → XP_017213744.2  sodium- and chloride-dependent GABA transporter 3

    UniProtKB/TrEMBL
    A0A8M6Z396
    Related
    ENSDARP00000142242.1, ENSDART00000173228.2
    Conserved Domains (1) summary
    cl00456
    Location:38 → 576
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein Strain
Heading Accession and Version

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