Gon7 GON7 subunit of KEOPS complex [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gon7provided by MGI
Official Full Name: GON7 subunit of KEOPS complexprovided by MGI
Primary source: MGI:MGI:4845848
See related: Ensembl:ENSMUSG00000091931 AllianceGenome:MGI:4845848
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Orthologous to human GON7 (GON7 subunit of KEOPS complex). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 14.8), CNS E14 (RPKM 10.5) and 28 other tissues See more
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Genomic context

Location:: 12 E; 12 52.14 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (102719534..102724069, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (102753275..102757810, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:236927

AA987038 (e-PCR)
- UniSTS:160247

Readthrough Gm20604

Readthrough gene: Gm20604, Included gene: Moap1

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in tRNA threonylcarbamoyladenosine modification	ISO Inferred from Sequence Orthology more info
involved_in tRNA threonylcarbamoyladenosine modification	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of EKC/KEOPS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of EKC/KEOPS complex	ISO Inferred from Sequence Orthology more info
part_of EKC/KEOPS complex	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: EKC/KEOPS complex subunit GON7

Names: GON7, KEOPS complex subunit homolog; uncharacterized protein C14orf142 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.