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si:ch73-105b23.6 si:ch73-105b23.6 [ Danio rerio (zebrafish) ]

Gene ID: 100332400, updated on 4-Jan-2025

Summary

Official Symbol
si:ch73-105b23.6provided by ZNC
Official Full Name
si:ch73-105b23.6provided by ZNC
Primary source
ZFIN:ZDB-GENE-081107-42
See related
AllianceGenome:ZFIN:ZDB-GENE-081107-42
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable calcium ion binding activity. Acts upstream of or within atrioventricular valve morphogenesis. Predicted to be located in extracellular region and membrane. Is expressed in atrioventricular canal. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human MUC4 (mucin 4, cell surface associated). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See si:ch73-105b23.6 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (8798218..8827782, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (8466679..8483920, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene si:ch211-93n23.7 Neighboring gene calmodulin 2a (phosphorylase kinase, delta) Neighboring gene fibrillin-2-like Neighboring gene epithelial cell adhesion molecule

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding  
Component Evidence Code Pubs
located_in extracellular region  
located_in membrane  

General protein information

Preferred Names
mucin-like protein; si:ch73-105b23.6
Names
novel EGF domain containing protein
zmp:0000000902

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    8798218..8827782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213002.1XP_068069103.1  mucin-like protein isoform X1

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395306.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    210795..225549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017358932.3XP_017214421.2  mucin-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8M6Z9Q8, E7FG10
    Conserved Domains (4) summary
    smart00179
    Location:487516
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:619647
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam12947
    Location:456485
    EGF_3; EGF domain
    cl02516
    Location:2171
    VWD; von Willebrand factor type D domain
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