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Zfp628 zinc finger protein 628 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100359484, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp628provided by RGD
Official Full Name
zinc finger protein 628provided by RGD
Primary source
RGD:2323809
See related
EnsemblRapid:ENSRNOG00000038622 AllianceGenome:RGD:2323809
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF628 (zinc finger protein 628). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 13.7), Kidney (RPKM 12.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp628 in Genome Data Viewer
Location:
1q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77942431..77950013, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68913600..68921186, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72465403..72474442, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene scavenger receptor cysteine rich family member with 5 domains Neighboring gene N-acetyltransferase 14 Neighboring gene similar to human chromosome 19 open reading frame 85 Neighboring gene isochorismatase domain containing 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ZEC, a zinc finger protein with novel binding specificity and transcription regulatory activity. Chen GY, et al. Gene, 2004 Sep 29. PMID 15556296
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 628

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401702.1 → NP_001388631.1  zinc finger protein 628

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    D3ZI74
    Related
    ENSRNOP00000030688.7, ENSRNOT00000029136.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    77942431..77950013 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039100601.2 → XP_038956529.1  zinc finger protein 628 isoform X3

    UniProtKB/TrEMBL
    D4A8F7
    Conserved Domains (3) summary
    COG5048
    Location:364 → 553
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:66 → 86
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:272 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_006228303.5 → XP_006228365.1  zinc finger protein 628 isoform X1

    See identical proteins and their annotated locations for XP_006228365.1

    UniProtKB/TrEMBL
    D3ZI74
    Conserved Domains (5) summary
    COG5048
    Location:23 → 221
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:148 → 168
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:354 → 371
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:615 → 637
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  3. XM_039100598.2 → XP_038956526.1  zinc finger protein 628 isoform X3

    UniProtKB/TrEMBL
    D4A8F7
    Conserved Domains (3) summary
    COG5048
    Location:364 → 553
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:66 → 86
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:272 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_039100593.2 → XP_038956521.1  zinc finger protein 628 isoform X2

    Related
    ENSRNOP00000104000.1, ENSRNOT00000136986.1
    Conserved Domains (3) summary
    COG5048
    Location:60 → 570
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:468 → 488
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:289 → 306
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_008759016.4 → XP_008757238.1  zinc finger protein 628 isoform X1

    See identical proteins and their annotated locations for XP_008757238.1

    UniProtKB/TrEMBL
    D3ZI74
    Related
    ENSRNOP00000082027.1, ENSRNOT00000116046.2
    Conserved Domains (5) summary
    COG5048
    Location:23 → 221
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:148 → 168
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:354 → 371
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:615 → 637
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  6. XM_063280976.1 → XP_063137046.1  zinc finger protein 628 isoform X1

    UniProtKB/TrEMBL
    D3ZI74

  7. XM_063281063.1 → XP_063137133.1  zinc finger protein 628 isoform X3

    UniProtKB/TrEMBL
    D4A8F7

  8. XM_063280967.1 → XP_063137037.1  zinc finger protein 628 isoform X1

    UniProtKB/TrEMBL
    D3ZI74
    Related
    ENSRNOP00000107204.1, ENSRNOT00000162199.1

  9. XM_039100605.2 → XP_038956533.1  zinc finger protein 628 isoform X3

    UniProtKB/TrEMBL
    D4A8F7
    Conserved Domains (3) summary
    COG5048
    Location:364 → 553
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:66 → 86
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:272 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]

  10. XM_017589974.3 → XP_017445463.1  zinc finger protein 628 isoform X1

    UniProtKB/TrEMBL
    D3ZI74
    Conserved Domains (5) summary
    COG5048
    Location:23 → 221
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:148 → 168
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:354 → 371
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:615 → 637
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  11. XM_063281027.1 → XP_063137097.1  zinc finger protein 628 isoform X1

    UniProtKB/TrEMBL
    D3ZI74

  12. XM_063281034.1 → XP_063137104.1  zinc finger protein 628 isoform X1

    UniProtKB/TrEMBL
    D3ZI74
Nucleotide Protein Strain
Heading Accession and Version

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