LOC100359876 multifunctional protein ADE2-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: LOC100359876provided by RGD
Full Name: multifunctional protein ADE2-likeprovided by RGD
Primary source: RGD:2323267
See related: AllianceGenome:RGD:2323267
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: AABR07036855.1
Summary: Predicted to enable ATP binding activity and phosphoribosylaminoimidazole carboxylase activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 612.2), Kidney (RPKM 595.7) and 9 other tissues See more
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (6635011..6636484)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (4032827..4034310)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (4285780..4287222)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables phosphoribosylaminoimidazole carboxylase activity	IEA Inferred from Electronic Annotation more info
enables phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in 'de novo' IMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in 'de novo' IMP biosynthetic process	IEA Inferred from Electronic Annotation more info

Preferred Names: bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase-like

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The following sections contain reference sequences that belong to a specific genome build. Explain