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Armc3 armadillo repeat containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100361506, updated on 4-Jan-2025

Summary

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Official Symbol
Armc3provided by RGD
Official Full Name
armadillo repeat containing 3provided by RGD
Primary source
RGD:2319961
See related
EnsemblRapid:ENSRNOG00000016716 AllianceGenome:RGD:2319961
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in flagellated sperm motility; ribophagy; and spermatid development. Orthologous to human ARMC3 (armadillo repeat containing 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 125.3), Kidney (RPKM 23.3) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Armc3 in Genome Data Viewer
Location:
17q12.3
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (86722436..86825899)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (81814087..81917534)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (85895841..86009403)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097847 Neighboring gene phosphatidylinositol-5-phosphate 4-kinase type 2 alpha Neighboring gene hypothetical LOC100361451 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene PICALM interacting mitotic regulator like 1 Neighboring gene uncharacterized LOC102556079 Neighboring gene uncharacterized LOC134482617 Neighboring gene methionine sulfoxide reductase B2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
  
involved_in ribophagy ISO
Inferred from Sequence Orthology
more info
  
involved_in spermatid development ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
armadillo repeat-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287020.1 → NP_001273949.1  armadillo repeat-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    M0R914
    Conserved Domains (5) summary
    cd00020
    Location:145 → 259
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam13646
    Location:152 → 258
    HEAT_2; HEAT repeats
    pfam14381
    Location:712 → 850
    EDR1; Ethylene-responsive protein kinase Le-CTR1
    sd00044
    Location:316 → 342
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:22 → 52
    ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    86722436..86825899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600429.3 → XP_017455918.1  armadillo repeat-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    M0R914
    Related
    ENSRNOP00000103893.1, ENSRNOT00000171634.1

  2. XM_017600428.3 → XP_017455917.1  armadillo repeat-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    M0R914
    Related
    ENSRNOP00000103410.1, ENSRNOT00000141115.1

  3. XM_017600430.3 → XP_017455919.1  armadillo repeat-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    M0R914

  4. XM_017600431.3 → XP_017455920.1  armadillo repeat-containing protein 3 isoform X4

    UniProtKB/TrEMBL
    A6JM99

  5. XM_063276004.1 → XP_063132074.1  armadillo repeat-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    M0R914

  6. XM_039095275.2 → XP_038951203.1  armadillo repeat-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    A6JM99
    Conserved Domains (5) summary
    smart00185
    Location:469 → 504
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:149 → 215
    PLN03200; cellulose synthase-interactive protein; Provisional
    COG5064
    Location:11 → 177
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:60 → 96
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:143 → 178
    Arm; Armadillo/beta-catenin-like repeat
Nucleotide Protein Strain
Heading Accession and Version

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