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Rnaseh2c ribonuclease H2, subunit C [ Rattus norvegicus (Norway rat) ]

Gene ID: 100361939, updated on 27-Nov-2024

Summary

Official Symbol
Rnaseh2cprovided by RGD
Official Full Name
ribonuclease H2, subunit Cprovided by RGD
Primary source
RGD:2319141
See related
EnsemblRapid:ENSRNOG00000020700 AllianceGenome:RGD:2319141
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in RNA catabolic process. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2C (ribonuclease H2 subunit C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 107.3), Spleen (RPKM 88.7) and 9 other tissues See more
Orthologs
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Genomic context

See Rnaseh2c in Genome Data Viewer
Location:
1q43
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212323916..212325011)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202894626..202895675)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220966626..220967717)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ovo like transcriptional repressor 1 Neighboring gene adaptor related protein complex 5 subunit beta 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene RELA proto-oncogene, NF-kB subunit

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in RNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in RNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of ribonuclease H2 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonuclease H2 complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ribonuclease H2 subunit C
Names
AYP1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401703.1NP_001388632.1  ribonuclease H2 subunit C

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6HZ77
    Related
    ENSRNOP00000028097.6, ENSRNOT00000028097.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    212323916..212325011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063282447.1XP_063138517.1  ribonuclease H2 subunit C isoform X1

    Related
    ENSRNOP00000105948.1, ENSRNOT00000124866.1