Slc2a7 solute carrier family 2 member 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc2a7provided by RGD
Official Full Name: solute carrier family 2 member 7provided by RGD
Primary source: RGD:1583902
See related: EnsemblRapid:ENSRNOG00000036951 AllianceGenome:RGD:1583902
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: GLUT-7
Summary: Predicted to enable D-glucose transmembrane transporter activity and fructose transmembrane transporter activity. Predicted to be involved in D-glucose transmembrane transport and fructose transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC2A7 (solute carrier family 2 member 7). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 1.1), Heart (RPKM 0.5) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (165907721..165927277)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (160624793..160643994)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (167195981..167211613)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables D-glucose transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-glucose transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
NOT enables D-glucose transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables D-glucose transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
NOT enables D-glucose transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables fructose transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
NOT enables fructose transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables fructose transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
NOT enables fructose transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in D-glucose import	IBA Inferred from Biological aspect of Ancestor more info
involved_in D-glucose transmembrane transport	IEA Inferred from Electronic Annotation more info
NOT involved_in D-glucose transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in D-glucose transmembrane transport	ISO Inferred from Sequence Orthology more info
NOT involved_in D-glucose transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in dehydroascorbic acid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in fructose transmembrane transport	IEA Inferred from Electronic Annotation more info
NOT involved_in fructose transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in fructose transmembrane transport	ISO Inferred from Sequence Orthology more info
NOT involved_in fructose transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: solute carrier family 2, facilitated glucose transporter member 7

Names: glucose transporter type 7; solute carrier family 2 (facilitated glucose transporter), member 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001393692.1 → NP_001380621.1 solute carrier family 2, facilitated glucose transporter member 7

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005

UniProtKB/TrEMBL

A6IUD0

Conserved Domains (1) summary

cd17432
Location:26 → 478

MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

165907721..165927277

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039111576.2 → XP_038967504.1 solute carrier family 2, facilitated glucose transporter member 7 isoform X1

UniProtKB/TrEMBL

A6IUD0, F1M868

Related

ENSRNOP00000052384.4, ENSRNOT00000055520.5

Conserved Domains (1) summary

cd17432
Location:26 → 490

MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001101020.1: Suppressed sequence

Description

NM_001101020.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.