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Sf3b6 splicing factor 3B, subunit 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100365504, updated on 27-Nov-2024

Summary

Official Symbol
Sf3b6provided by RGD
Official Full Name
splicing factor 3B, subunit 6provided by RGD
Primary source
RGD:2318878
See related
EnsemblRapid:ENSRNOG00000046172 AllianceGenome:RGD:2318878
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within blastocyst formation. Predicted to be located in nucleoplasm. Predicted to be part of U2 snRNP and spliceosomal complex. Orthologous to human SF3B6 (splicing factor 3b subunit 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 271.5), Kidney (RPKM 198.1) and 9 other tissues See more
Orthologs
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Genomic context

See Sf3b6 in Genome Data Viewer
Location:
6q14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (33545495..33554537)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (27826044..27835086)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (29991232..29999668, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene profilin family, member 4 Neighboring gene tumor protein p53 inducible protein 3 Neighboring gene FKBP prolyl isomerase 1B Neighboring gene U6 spliceosomal RNA Neighboring gene WD repeat and coiled coil containing Neighboring gene MFSD2 lysolipid transporter B, sphingolipid

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within blastocyst formation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
splicing factor 3B subunit 6
Names
splicing factor 3B, 14 kDa subunit-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271222.1NP_001258151.1  splicing factor 3B subunit 6

    See identical proteins and their annotated locations for NP_001258151.1

    Status: VALIDATED

    Source sequence(s)
    FM089942, FM108041, FM109760
    UniProtKB/TrEMBL
    A0A8I6AFT8, A6HAJ3, M0R835
    Related
    ENSRNOP00000091764.1, ENSRNOT00000110429.2
    Conserved Domains (1) summary
    cd12241
    Location:1793
    RRM_SF3B14; RNA recognition motif (RRM) found in pre-mRNA branch site protein p14 (SF3B14) and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    33545495..33554537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)