Zfp965 zinc finger protein 965 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp965provided by MGI
Official Full Name: zinc finger protein 965provided by MGI
Primary source: MGI:MGI:3779822
See related: Ensembl:ENSMUSG00000078896 AllianceGenome:MGI:3779822
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 668009; Gm8923
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to human ZNF559-ZNF177 (ZNF559-ZNF177 readthrough). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in bladder adult (RPKM 5.6), cerebellum adult (RPKM 4.6) and 25 other tissues See more
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Genomic context

Location:: 2 H4; 2 98.44 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (175311818..175322346)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (175470025..175480553)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: KRAB box and zinc finger, C2H2 type domain containing protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001242944.1 → NP_001229873.1 KRAB box and zinc finger, C2H2 type domain containing protein-like

See identical proteins and their annotated locations for NP_001229873.1

Status: VALIDATED

Source sequence(s)

CT010482

Consensus CDS

CCDS79872.1

UniProtKB/TrEMBL

A2BE20

Related

ENSMUSP00000104630.3, ENSMUST00000109002.9

Conserved Domains (5) summary

smart00349
Location:23 → 64

KRAB; krueppel associated box

COG5048
Location:43 → 302

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:180 → 200

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:23 → 62

KRAB; KRAB box

pfam13465
Location:192 → 217

zf-H2C2_2; Zinc-finger double domain