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Cmtm1 CKLF-like MARVEL transmembrane domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 100504164, updated on 27-Nov-2024

Summary

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Official Symbol
Cmtm1provided by MGI
Official Full Name
CKLF-like MARVEL transmembrane domain containing 1provided by MGI
Primary source
MGI:MGI:2447159
See related
Ensembl:ENSMUSG00000110430 AllianceGenome:MGI:2447159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CKLFH; CKLFH1; CHLFH1a; Cklfsf1
Summary
Predicted to be active in membrane. Orthologous to human CMTM1 (CKLF like MARVEL transmembrane domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 35.0) See more
Orthologs
human all
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Genomic context

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See Cmtm1 in Genome Data Viewer
Location:
8 D3; 8 53.04 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (105020174..105036777, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (104293542..104310145, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene chemokine-like factor Neighboring gene STARR-seq mESC enhancer starr_22506 Neighboring gene CKLF-like MARVEL transmembrane domain containing 2A Neighboring gene predicted gene 45710 Neighboring gene CKLF-like MARVEL transmembrane domain containing 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice. Fujihara Y, et al. J Cell Sci, 2018 Oct 8. PMID 30209135, Free PMC Article
  2. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Han W, et al. Genomics, 2003 Jun. PMID 12782130
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CKLF-like MARVEL transmembrane domain-containing protein 1
Names
chemokine-like factor super family 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181990.2 → NP_871790.2  CKLF-like MARVEL transmembrane domain-containing protein 1

    See identical proteins and their annotated locations for NP_871790.2

    Status: VALIDATED

    Source sequence(s)
    AC121275, AC121952
    Consensus CDS
    CCDS57636.1
    UniProtKB/TrEMBL
    B7ZP21
    Related
    ENSMUSP00000124855.2, ENSMUST00000159039.2
    Conserved Domains (2) summary
    pfam01284
    Location:172 → 274
    MARVEL; Membrane-associating domain
    pfam07001
    Location:30 → 108
    BAT2_N; BAT2 N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    105020174..105036777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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