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PDK4 pyruvate dehydrogenase kinase 4 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100674220, updated on 11-Apr-2024

Summary

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Gene symbol
PDK4
Gene description
pyruvate dehydrogenase kinase 4
See related
EnsemblRapid:ENSLAFG00000011165
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See PDK4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 8 NC_087349.1 (65242782..65255583, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573425.1 (53988771..54000338)

Chromosome 8 - NC_087349.1Genomic Context describing neighboring genes Neighboring gene paraoxonase 2 Neighboring gene ankyrin repeat and SOCS box containing 4 Neighboring gene dynein cytoplasmic 1 intermediate chain 1 Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene solute carrier family 25 member 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate dehydrogenase kinase, isozyme 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087349.1 Reference mLoxAfr1.hap2

    Range
    65242782..65255583 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064289996.1 → XP_064146066.1  pyruvate dehydrogenase kinase, isozyme 4 isoform X2

  2. XM_003407128.4 → XP_003407176.1  pyruvate dehydrogenase kinase, isozyme 4 isoform X1

    UniProtKB/TrEMBL
    G3T703
    Related
    ENSLAFP00000009346.3, ENSLAFT00000011167.4
    Conserved Domains (3) summary
    smart00387
    Location:245 → 365
    HATPase_c; Histidine kinase-like ATPases
    COG0642
    Location:245 → 373
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
    pfam10436
    Location:34 → 195
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  3. XM_023544404.2 → XP_023400172.1  pyruvate dehydrogenase kinase, isozyme 4 isoform X3

    Conserved Domains (2) summary
    smart00387
    Location:149 → 269
    HATPase_c; Histidine kinase-like ATPases
    pfam10436
    Location:1 → 99
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
Nucleotide Protein
Heading Accession and Version

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