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KCNH5 potassium voltage-gated channel subfamily H member 5 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100674999, updated on 11-Apr-2024

Summary

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Gene symbol
KCNH5
Gene description
potassium voltage-gated channel subfamily H member 5
See related
EnsemblRapid:ENSLAFG00000005188
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See KCNH5 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 10 NC_087351.1 (74702387..75038713, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573429.1 (38363798..38703566, complement)

Chromosome 10 - NC_087351.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin 16 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111750161 Neighboring gene ras homolog family member J Neighboring gene glycoprotein hormone subunit beta 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
potassium voltage-gated channel subfamily H member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087351.1 Reference mLoxAfr1.hap2

    Range
    74702387..75038713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003408696.4 → XP_003408744.1  potassium voltage-gated channel subfamily H member 5

    UniProtKB/TrEMBL
    G3SVQ7
    Related
    ENSLAFP00000004341.3, ENSLAFT00000005188.4
    Conserved Domains (6) summary
    COG0664
    Location:544 → 725
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    cd00038
    Location:550 → 660
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd00130
    Location:37 → 131
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00520
    Location:232 → 479
    Ion_trans; Ion transport protein
    pfam07885
    Location:419 → 473
    Ion_trans_2; Ion channel
    pfam08447
    Location:40 → 127
    PAS_3; PAS fold
Nucleotide Protein
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