U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ndufb1 NADH:ubiquinone oxidoreductase subunit B1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100912357, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Ndufb1provided by RGD
Official Full Name
NADH:ubiquinone oxidoreductase subunit B1provided by RGD
Primary source
RGD:6487218
See related
EnsemblRapid:ENSRNOG00000088065 AllianceGenome:RGD:6487218
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
CI-MNLL
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and nuclear speck. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFB1 (NADH:ubiquinone oxidoreductase subunit B1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 1460.3), Muscle (RPKM 1177.4) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ndufb1 in Genome Data Viewer
Location:
6q32
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (126880537..126888935, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (121115649..121124055, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (125861219..125870231, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103604 Neighboring gene ribosomal protein L37A, pseudogene 6 Neighboring gene uncharacterized LOC134479251 Neighboring gene ataxin 3 Neighboring gene LLP homolog, long-term synaptic facilitation factor, pseudogene 1 Neighboring gene cleavage and polyadenylation specific factor 2 Neighboring gene solute carrier family 24 member 4 Neighboring gene Ras and Rab interactor 3 Neighboring gene uncharacterized LOC134479252

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Stroud DA, et al. Nature, 2016 Oct 6. PMID 27626371
  2. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. Murray J, et al. J Biol Chem, 2003 Apr 18. PMID 12611891
  3. Architecture of Human Mitochondrial Respiratory Megacomplex I(2)III(2)IV(2). Guo R, et al. Cell, 2017 Sep 7. PMID 28844695
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial respiratory chain complex I assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
  
part_of respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Names
Complex I-MNLL
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
NADH-ubiquinone oxidoreductase MNLL subunit

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001402546.1 → NP_001389475.1  nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    P0DN35
    UniProtKB/TrEMBL
    A6JEJ6
    Related
    ENSRNOP00000109926.1, ENSRNOT00000153359.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    126880537..126888935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056985555.2 → XP_056841535.1  nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 isoform X1

    UniProtKB/Swiss-Prot
    P0DN35
    UniProtKB/TrEMBL
    A6JEJ6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DN35.1 GenPept UniProtKB/Swiss-Prot:P0DN35

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.