U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lilrb1 leukocyte immunoglobulin like receptor B1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100912456, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Symbol
Lilrb1provided by RGD
Full Name
leukocyte immunoglobulin like receptor B1provided by RGD
Primary source
RGD:6487069
See related
AllianceGenome:RGD:6487069
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable inhibitory MHC class I receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and immune response-regulating signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 54.7), Lung (RPKM 34.9) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Lilrb1 in Genome Data Viewer
Location:
1q12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (74372772..74379871)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (65457264..65464523)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (63883684..63891697)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene paired-Ig-like receptor A2 Neighboring gene small nuclear ribonucleoprotein polypeptide C, pseudogene 4 Neighboring gene constitutive coactivator of PPAR-gamma-like protein 1 Neighboring gene paired Ig-like receptor B Neighboring gene ribosomal protein S9 Neighboring gene tRNA splicing endonuclease subunit 34

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables inhibitory MHC class I receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in cytokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response-regulating signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 3-like
Names
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    74372772..74379871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228040.5 → XP_006228102.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X3

    See identical proteins and their annotated locations for XP_006228102.1

    Conserved Domains (2) summary
    smart00410
    Location:530 → 617
    IG_like; Immunoglobulin like
    cl11960
    Location:225 → 315
    Ig; Immunoglobulin domain

  2. XM_003748711.6 → XP_003748759.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X1

    See identical proteins and their annotated locations for XP_003748759.1

    UniProtKB/TrEMBL
    A0A0G2JYU1
    Conserved Domains (2) summary
    smart00410
    Location:530 → 617
    IG_like; Immunoglobulin like
    cl11960
    Location:225 → 315
    Ig; Immunoglobulin domain

  3. XM_006228039.5 → XP_006228101.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X2

    See identical proteins and their annotated locations for XP_006228101.1

    UniProtKB/TrEMBL
    A0A0G2KAU3, A0A8I6AZE5
    Conserved Domains (2) summary
    smart00410
    Location:530 → 617
    IG_like; Immunoglobulin like
    cl11960
    Location:225 → 315
    Ig; Immunoglobulin domain

  4. XM_006228042.5 → XP_006228104.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X4

    See identical proteins and their annotated locations for XP_006228104.1

    Conserved Domains (2) summary
    smart00410
    Location:465 → 552
    IG_like; Immunoglobulin like
    cl11960
    Location:160 → 250
    Ig; Immunoglobulin domain

  5. XM_039100379.2 → XP_038956307.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X6

    Conserved Domains (3) summary
    cd00096
    Location:331 → 334
    Ig; Ig strand A' [structural motif]
    cd16843
    Location:225 → 314
    IgC2_D1_D2_LILR_KIR_like; Immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors, Natural killer inhibitory receptors (KIRs) and similar domains; member of Immunoglobulin Constant-2 set of IgSF domains
    cl11960
    Location:325 → 417
    Ig; Immunoglobulin domain

  6. XM_063280906.1 → XP_063136976.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X5

RNA

  1. XR_010062963.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.