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Zfp575 zinc finger protein 575 [ Mus musculus (house mouse) ]

Gene ID: 101544, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp575provided by MGI
Official Full Name
zinc finger protein 575provided by MGI
Primary source
MGI:MGI:2141921
See related
Ensembl:ENSMUSG00000066721 AllianceGenome:MGI:2141921
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf575
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF575 (zinc finger protein 575). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 2.3), whole brain E14.5 (RPKM 2.1) and 18 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp575 in Genome Data Viewer
Location:
7 A3; 7 11.63 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24283942..24287049, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24583838..24587840, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18269 Neighboring gene phospholipase A2 inhibitor and LY6/PLAUR domain containing Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 1 Neighboring gene ethylmalonic encephalopathy 1 Neighboring gene STARR-seq mESC enhancer starr_18271 Neighboring gene STARR-positive B cell enhancer ABC_E4903 Neighboring gene pleckstrin homology like domain, family B, member 3 Neighboring gene predicted gene, 26550 Neighboring gene Ly6/Plaur domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription. An N, et al. Oncol Res, 2023. PMID 37305392, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription.
    Title: The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 575

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033205.4 → NP_001028377.1  zinc finger protein 575

    See identical proteins and their annotated locations for NP_001028377.1

    Status: VALIDATED

    Source sequence(s)
    AC161166
    Consensus CDS
    CCDS20956.1
    UniProtKB/Swiss-Prot
    Q3TXZ1
    UniProtKB/TrEMBL
    B2RX29
    Related
    ENSMUSP00000092294.3, ENSMUST00000094705.3
    Conserved Domains (1) summary
    sd00017
    Location:87 → 107
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001419146.1 → NP_001406075.1  zinc finger protein 575

    Status: VALIDATED

    Source sequence(s)
    AC161166
    UniProtKB/Swiss-Prot
    Q3TXZ1
    UniProtKB/TrEMBL
    B2RX29

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    24283942..24287049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TXZ1.1 GenPept UniProtKB/Swiss-Prot:Q3TXZ1

Gene LinkOut

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