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Acp7 acid phosphatase 7, tartrate resistant [ Mus musculus (house mouse) ]

Gene ID: 101744, updated on 27-Nov-2024

Summary

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Official Symbol
Acp7provided by MGI
Official Full Name
acid phosphatase 7, tartrate resistantprovided by MGI
Primary source
MGI:MGI:2142121
See related
Ensembl:ENSMUSG00000037469 AllianceGenome:MGI:2142121
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Papl; C330005M16Rik
Summary
Predicted to enable acid phosphatase activity and metal ion binding activity. Predicted to be located in extracellular region. Orthologous to human ACP7 (acid phosphatase 7, tartrate resistant (putative)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in stomach adult (RPKM 3.5), testis adult (RPKM 2.1) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Acp7 in Genome Data Viewer
Location:
7 B1; 7 16.86 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28304055..28330755, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28607322..28631332, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29342572-29342755 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29342797-29343021 Neighboring gene predicted gene, 38977 Neighboring gene microRNA 7049 Neighboring gene p21 (RAC1) activated kinase 4 Neighboring gene STARR-seq mESC enhancer starr_18428 Neighboring gene STARR-seq mESC enhancer starr_18429 Neighboring gene STARR-seq mESC enhancer starr_18430 Neighboring gene STARR-seq mESC enhancer starr_18432 Neighboring gene STARR-seq mESC enhancer starr_18434 Neighboring gene F-box protein 27 Neighboring gene F-box protein 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acid phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acid phosphatase type 7
Names
iron/zinc purple acid phospatase-like
iron/zinc purple acid phosphatase-like protein
purple acid phosphatase long form
NP_780528.2
XP_006539510.1
XP_006539512.1
XP_006539513.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175319.5 → NP_780528.2  acid phosphatase type 7 precursor

    Status: VALIDATED

    Source sequence(s)
    AC109162, AC136456
    Consensus CDS
    CCDS21050.2
    UniProtKB/Swiss-Prot
    Q8BX37
    Related
    ENSMUSP00000159320.2, ENSMUST00000239470.2
    Conserved Domains (2) summary
    cd00839
    Location:131 → 429
    MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
    pfam16656
    Location:32 → 124
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28304055..28330755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539449.5 → XP_006539512.1  acid phosphatase type 7 isoform X1

    See identical proteins and their annotated locations for XP_006539512.1

    UniProtKB/TrEMBL
    B2RRA7
    Conserved Domains (2) summary
    cd00839
    Location:189 → 487
    MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
    pfam16656
    Location:90 → 182
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

  2. XM_006539447.5 → XP_006539510.1  acid phosphatase type 7 isoform X1

    See identical proteins and their annotated locations for XP_006539510.1

    UniProtKB/TrEMBL
    B2RRA7
    Related
    ENSMUSP00000045437.4, ENSMUST00000040112.5
    Conserved Domains (2) summary
    cd00839
    Location:189 → 487
    MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
    pfam16656
    Location:90 → 182
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

  3. XM_006539450.3 → XP_006539513.1  acid phosphatase type 7 isoform X2

    See identical proteins and their annotated locations for XP_006539513.1

    UniProtKB/Swiss-Prot
    Q8BX37
    Related
    ENSMUSP00000147133.3, ENSMUST00000159560.3
    Conserved Domains (2) summary
    cd00839
    Location:131 → 429
    MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
    pfam16656
    Location:32 → 124
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BX37.2 GenPept UniProtKB/Swiss-Prot:Q8BX37

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