U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LINC01186 long intergenic non-protein coding RNA 1186 [ Homo sapiens (human) ]

Gene ID: 101927574, updated on 17-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
LINC01186provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1186provided by HGNC
Primary source
HGNC:HGNC:49573
See related
AllianceGenome:HGNC:49573
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF674-1
Expression
Broad expression in fat (RPKM 1.2), duodenum (RPKM 0.6) and 15 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LINC01186 in Genome Data Viewer
Location:
Xp11.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (46325924..46327674, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (45733177..45734927, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (46185359..46187109, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene proliferating cell nuclear antigen pseudogene 3 Neighboring gene NANOG hESC enhancer GRCh37_chrX:46114084-46114585 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:46122614-46123813 Neighboring gene ACTB pseudogene 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:46186381-46187580 Neighboring gene CTNNBL1 pseudogene 1 Neighboring gene glyceraldehyde 3 phosphate dehydrogenase pseudogene 65

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Long noncoding RNA LINC01186, regulated by TGF-β/SMAD3, inhibits migration and invasion through Epithelial-Mesenchymal-Transition in lung cancer. Hao Y, et al. Gene, 2017 Apr 15. PMID 28119085

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01186, a mediator of TGF-beta signaling, can play a significant role in the regulation of epithelial-mesenchymal transition and lung cancer cell migration and invasion.
    Title: Long noncoding RNA LINC01186, regulated by TGF-β/SMAD3, inhibits migration and invasion through Epithelial-Mesenchymal-Transition in lung cancer.
Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110388.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL700385, DW451179

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    46325924..46327674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    45733177..45734927 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials