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Lnclep long noncoding RNA upstream of leptin [ Mus musculus (house mouse) ]

Gene ID: 102632876, updated on 9-Dec-2024

Summary

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Official Symbol
Lnclepprovided by MGI
Official Full Name
long noncoding RNA upstream of leptinprovided by MGI
Primary source
MGI:MGI:5589997
See related
AllianceGenome:MGI:5589997
Gene type
ncRNA
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lnc-; LncOb; Gm30838; Lnc-leptin
Summary
Acts upstream of or within with a positive effect on white fat cell differentiation. Acts upstream of or within cellular response to insulin stimulus; fat cell differentiation; and gene expression. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Lnclep in Genome Data Viewer
Location:
6 A3.3; 6
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (29030953..29039526)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (29030954..29039527)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38779 Neighboring gene predicted gene, 40357 Neighboring gene uncharacterized LOC118567373 Neighboring gene STARR-seq mESC enhancer starr_15429 Neighboring gene microRNA 129-1 Neighboring gene Lep proximal promoter region Neighboring gene leptin Neighboring gene predicted gene, 25589

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity. Dallner OS, et al. Nat Med, 2019 Mar. PMID 30842678
  2. Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin. Lo KA, et al. Diabetes, 2018 Jun. PMID 29519872

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to insulin stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within fat cell differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to insulin IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within_positive_effect white fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    29030953..29039526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_377380.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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