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Gm14296 predicted gene 14296 [ Mus musculus (house mouse) ]

Gene ID: 102639598, updated on 4-Jan-2025

Summary

Official Symbol
Gm14296provided by MGI
Official Full Name
predicted gene 14296provided by MGI
Primary source
MGI:MGI:3708667
See related
Ensembl:ENSMUSG00000074527 AllianceGenome:MGI:3708667
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable sequence-specific double-stranded DNA binding activity. Orthologous to human ZNF559-ZNF177 (ZNF559-ZNF177 readthrough). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in cortex adult (RPKM 2.5), cerebellum adult (RPKM 2.5) and 25 other tissues See more
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Genomic context

See Gm14296 in Genome Data Viewer
Location:
2 H4; 2 99.11 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (176584302..176619606, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (176892509..176927813, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14408 Neighboring gene predicted gene 14405 Neighboring gene zinc finger protein 930 pseudogene Neighboring gene zinc finger protein 120-like Neighboring gene predicted gene 14419

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
uncharacterized protein LOC102639598
Names
novel KRAB box and zinc finger, C2H2 type domain containing protein
zinc finger protein 431-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305132.1NP_001292061.1  uncharacterized protein LOC102639598 isoform 1

    See identical proteins and their annotated locations for NP_001292061.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL845456
    Consensus CDS
    CCDS79875.1
    UniProtKB/TrEMBL
    A2ARL4
    Related
    ENSMUSP00000096605.3, ENSMUST00000099007.3
    Conserved Domains (5) summary
    smart00349
    Location:445
    KRAB; krueppel associated box
    COG5048
    Location:74133
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:7997
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:89114
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001305133.1NP_001292062.1  uncharacterized protein LOC102639598 isoform 2

    See identical proteins and their annotated locations for NP_001292062.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 5' region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1.
    Source sequence(s)
    AL845456
    UniProtKB/TrEMBL
    D3YYR3
    Conserved Domains (2) summary
    sd00017
    Location:4765
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:5782
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_130970.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon and contains two alternate 3' exons, compared to variant 1. This variant is represented as non-coding because the use of the translational start codon used in variant 1 renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL845456
    Related
    ENSMUST00000134982.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    176584302..176619606 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080980.1: Suppressed sequence

    Description
    NM_001080980.1: This RefSeq was permanently suppressed because it was mostly repetitive sequence.
  2. NM_029813.2: Suppressed sequence

    Description
    NM_029813.2: This RefSeq was permanently suppressed because it was mostly repetitive sequence.
  3. NM_172929.2: Suppressed sequence

    Description
    NM_172929.2: This RefSeq was permanently suppressed because it was mostly repetitive sequence.