U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 103693257, updated on 4-Jan-2025

Summary

Symbol
Ercc4l1provided by RGD
Full Name
excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1provided by RGD
Primary source
RGD:1304845
See related
EnsemblRapid:ENSRNOG00000070542 AllianceGenome:RGD:1304845
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ercc4
Summary
Predicted to enable damaged DNA binding activity; single-stranded DNA binding activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination; nucleotide-excision repair involved in interstrand cross-link repair; and resolution of meiotic recombination intermediates. Predicted to be part of nucleotide-excision repair factor 1 complex. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 79.5), Brain (RPKM 69.8) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ercc4l1 in Genome Data Viewer
Location:
10q11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (1462146..1500409)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (954927..983651)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (975653..1010029)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene microRNA 484 Neighboring gene meiosis regulator and mRNA stability factor 1 Neighboring gene myocardin related transcription factor B Neighboring gene transfer RNA threonine (anticodon CGU) 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables single-stranded DNA endodeoxyribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nucleotide-excision repair involved in interstrand cross-link repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in resolution of meiotic recombination intermediates IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of nucleotide-excision repair factor 1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
DNA repair endonuclease XPF
Names
DNA repair endonuclease XPF-like
excision repair cross-complementing rodent repair deficiency, complementation group 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    1462146..1500409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270016.1XP_063126086.1  DNA repair endonuclease XPF

    UniProtKB/TrEMBL
    A0A0G2K855
    Related
    ENSRNOP00000074477.3, ENSRNOT00000089404.3