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Vmac vimentin-type intermediate filament associated coiled-coil protein [ Mus musculus (house mouse) ]

Gene ID: 106639, updated on 27-Nov-2024

Summary

Official Symbol
Vmacprovided by MGI
Official Full Name
vimentin-type intermediate filament associated coiled-coil proteinprovided by MGI
Primary source
MGI:MGI:2146912
See related
Ensembl:ENSMUSG00000054723 AllianceGenome:MGI:2146912
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in cytoplasm. Predicted to be active in type III intermediate filament. Orthologous to human VMAC (vimentin type intermediate filament associated coiled-coil protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 20.2), adrenal adult (RPKM 18.8) and 27 other tissues See more
Orthologs
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Genomic context

See Vmac in Genome Data Viewer
Location:
17 D; 17 29.47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (57020936..57024688, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56713932..56717699, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene predicted gene, 33461 Neighboring gene STARR-seq mESC enhancer starr_42897 Neighboring gene RAN binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_42898 Neighboring gene STARR-positive B cell enhancer ABC_E962 Neighboring gene calcyphosine, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit A11 Neighboring gene fucosyltransferase 4, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in type III intermediate filament IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in type III intermediate filament ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
vimentin-type intermediate filament-associated coiled-coil protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166474.2NP_001159946.1  vimentin-type intermediate filament-associated coiled-coil protein isoform 2

    See identical proteins and their annotated locations for NP_001159946.1

    Status: VALIDATED

    Source sequence(s)
    CT010491
    Consensus CDS
    CCDS50154.1
    UniProtKB/TrEMBL
    G3XA49
    Related
    ENSMUSP00000132817.2, ENSMUST00000164907.3
  2. NM_178926.4NP_849257.1  vimentin-type intermediate filament-associated coiled-coil protein isoform 1

    See identical proteins and their annotated locations for NP_849257.1

    Status: VALIDATED

    Source sequence(s)
    CT010491
    Consensus CDS
    CCDS28912.1
    UniProtKB/Swiss-Prot
    Q3UKV2, Q8BP01
    Related
    ENSMUSP00000064120.6, ENSMUST00000067931.7
    Conserved Domains (1) summary
    pfam15272
    Location:35113
    BBP1_C; Spindle pole body component BBP1, C-terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    57020936..57024688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)