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Mrpl30 mitochondrial ribosomal protein L30 [ Mus musculus (house mouse) ]

Gene ID: 107734, updated on 27-Nov-2024

Summary

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Official Symbol
Mrpl30provided by MGI
Official Full Name
mitochondrial ribosomal protein L30provided by MGI
Primary source
MGI:MGI:1333820
See related
Ensembl:ENSMUSG00000026087 AllianceGenome:MGI:1333820
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L30mt; Rpml28; MRP-L28; MRP-L30; 2310001L22Rik
Summary
Predicted to be a structural constituent of ribosome. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL30 (mitochondrial ribosomal protein L30). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in heart adult (RPKM 15.4), liver E14 (RPKM 13.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Mrpl30 in Genome Data Viewer
Location:
1 B; 1 16.17 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (37929558..37937419)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37890477..37898338)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene testis specific 10 Neighboring gene STARR-seq mESC enhancer starr_00684 Neighboring gene STARR-positive B cell enhancer mm9_chr1:37921599-37921900 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37922129-37922238 Neighboring gene lipoyltransferase 1 Neighboring gene MIT, microtubule interacting and transport, domain containing 1 Neighboring gene lysozyme G-like 2 Neighboring gene STARR-seq mESC enhancer starr_00687 Neighboring gene lysozyme G-like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. Goldschmidt-Reisin S, et al. J Biol Chem, 1998 Dec 25. PMID 9857009
  2. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
  5. The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes. Liu F, et al. Mol Cell Proteomics, 2018 Feb. PMID 29222160, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrial ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL30m
Names
39S ribosomal protein L30, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356482.2 → NP_001343411.1  large ribosomal subunit protein uL30m precursor

    Status: VALIDATED

    Source sequence(s)
    AC119189
    Consensus CDS
    CCDS14896.1
    UniProtKB/Swiss-Prot
    Q99KJ7, Q9D7N6
    UniProtKB/TrEMBL
    A0A0A6YXW4
    Related
    ENSMUSP00000141654.2, ENSMUST00000193673.6
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...

  2. NM_027098.4 → NP_081374.1  large ribosomal subunit protein uL30m precursor

    See identical proteins and their annotated locations for NP_081374.1

    Status: VALIDATED

    Source sequence(s)
    AC119189
    Consensus CDS
    CCDS14896.1
    UniProtKB/Swiss-Prot
    Q99KJ7, Q9D7N6
    UniProtKB/TrEMBL
    A0A0A6YXW4
    Related
    ENSMUSP00000027256.6, ENSMUST00000027256.12
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    37929558..37937419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238417.3 → XP_011236719.1  large ribosomal subunit protein uL30m isoform X1

    See identical proteins and their annotated locations for XP_011236719.1

    UniProtKB/Swiss-Prot
    Q99KJ7, Q9D7N6
    UniProtKB/TrEMBL
    A0A0A6YXW4
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D7N6.1 GenPept UniProtKB/Swiss-Prot:Q9D7N6

Gene LinkOut

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