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aldh5a1.S aldehyde dehydrogenase 5 family member A1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108720127, updated on 4-Nov-2024

Summary

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Official Symbol
aldh5a1.S
Official Full Name
aldehyde dehydrogenase 5 family member A1 S homeolog
Primary source
Xenbase:XB-GENE-17346769
Locus tag
XELAEV_18033511mg
See related
EnsemblRapid:ENSXLAG00005016547 AllianceGenome:Xenbase:XB-GENE-17346769
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable succinate-semialdehyde dehydrogenase (NAD+) activity. Predicted to act upstream of or within gamma-aminobutyric acid catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in succinic semialdehyde dehydrogenase deficiency. Orthologous to human ALDH5A1 (aldehyde dehydrogenase 5 family member A1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See aldh5a1.S in Genome Data Viewer
Location:
chromosome: 6S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (82745099..82763850)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (74606243..74625299)

Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene neurensin 1 S homeolog Neighboring gene doublecortin domain containing 2 S homeolog Neighboring gene KIAA0319 S homeolog Neighboring gene tyrosyl-DNA phosphodiesterase 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables succinate-semialdehyde dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables succinate-semialdehyde dehydrogenase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within gamma-aminobutyric acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
succinate-semialdehyde dehydrogenase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    82745099..82763850
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018269522.2 → XP_018125011.1  succinate-semialdehyde dehydrogenase, mitochondrial

    UniProtKB/TrEMBL
    A0A8J0VM74, A0A974CJG2
    Related
    ENSXLAP00005048672.1, ENSXLAT00005049809.1
Nucleotide Protein Strain
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