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ripor2.S RHO family interacting cell polarization regulator 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108720134, updated on 4-Nov-2024

Summary

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Official Symbol
ripor2.S
Official Full Name
RHO family interacting cell polarization regulator 2 S homeolog
Primary source
Xenbase:XB-GENE-6489256
Locus tag
XELAEV_18033519mg
See related
EnsemblRapid:ENSXLAG00005017194 AllianceGenome:Xenbase:XB-GENE-6489256
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fam65b; fam65b.S
Summary
Predicted to act upstream of or within several processes, including chemotaxis; muscle organ development; and sensory perception of sound. Predicted to be located in several cellular components, including apical plasma membrane; filopodium; and stereocilium membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 21 and autosomal recessive nonsyndromic deafness 104. Orthologous to human RIPOR2 (RHO family interacting cell polarization regulator 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ripor2.S in Genome Data Viewer
Location:
chromosome: 6S
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (83241992..83353529)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (74988418..75120513)

Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene secretagogin, EF-hand calcium binding protein S homeolog Neighboring gene capping protein regulator and myosin 1 linker 1 S homeolog Neighboring gene chromosome 6 C6orf62 homolog S homeolog Neighboring gene geminin, DNA replication inhibitor S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chemotaxis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within muscle organ development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sensory perception of sound IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in filopodium IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in stereocilium membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rho family-interacting cell polarization regulator 2
Names
family with sequence similarity 65 member B S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    83241992..83353529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041567770.1 → XP_041423704.1  rho family-interacting cell polarization regulator 2 isoform X3

    UniProtKB/TrEMBL
    A0A8J1L401, A0A974HFX2

  2. XM_018269534.2 → XP_018125023.1  rho family-interacting cell polarization regulator 2 isoform X1

    UniProtKB/TrEMBL
    A0A8J0VKA8, A0A974HFX2
    Related
    ENSXLAP00005050761.1, ENSXLAT00005051918.1

  3. XM_018269532.2 → XP_018125021.1  rho family-interacting cell polarization regulator 2 isoform X5

    UniProtKB/TrEMBL
    A0A8J0VMJ9, A0A974HFX2
    Related
    ENSXLAP00005050770.1, ENSXLAT00005051929.1

  4. XM_041567769.1 → XP_041423703.1  rho family-interacting cell polarization regulator 2 isoform X2

    UniProtKB/TrEMBL
    A0A8J1L2D5, A0A974HFX2
    Related
    ENSXLAP00005050733.1, ENSXLAT00005051890.1

  5. XM_041567771.1 → XP_041423705.1  rho family-interacting cell polarization regulator 2 isoform X4

    UniProtKB/TrEMBL
    A0A1L8FSG7, A0A974HEH7, A0A974HFX2
    Related
    ENSXLAP00005050702.1, ENSXLAT00005051859.1
    Conserved Domains (1) summary
    pfam15903
    Location:16 → 364
    PL48; Filopodia upregulated, FAM65
Nucleotide Protein Strain
Heading Accession and Version

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