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Adam2 ADAM metallopeptidase domain 2 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110309160, updated on 15-Mar-2024

Summary

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Gene symbol
Adam2
Gene description
ADAM metallopeptidase domain 2
See related
Ensembl:MGP_CAROLIEiJ_G0019434
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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See Adam2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
21
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 14 NC_034583.1 (57181801..57232566, complement)

Chromosome 14 - NC_034583.1Genomic Context describing neighboring genes Neighboring gene L-gulonolactone oxidase Neighboring gene clusterin Neighboring gene epoxide hydrolase 2 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034583.1 Chromosome 14 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Positive selection in the adhesion domain of Mus sperm Adam genes through gene duplications and function-driven gene complex formations. Grayson P, et al. BMC Evol Biol, 2013 Sep 30. PMID 24079728, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in binding of sperm to zona pellucida IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 2
Names
a disintegrin and metallopeptidase domain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034583.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    57181801..57232566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021181627.1 → XP_021037286.1  disintegrin and metalloproteinase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5QSE9
    Related
    MGP_CAROLIEiJ_P0037168, MGP_CAROLIEiJ_T0037168.1
    Conserved Domains (4) summary
    smart00050
    Location:398 → 473
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:475 → 610
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:184 → 381
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:32 → 147
    Pep_M12B_propep; Reprolysin family propeptide

  2. XM_021181629.1 → XP_021037288.1  disintegrin and metalloproteinase domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P5QZP1
    Conserved Domains (4) summary
    smart00050
    Location:391 → 466
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:468 → 603
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:177 → 374
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:25 → 140
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein
Heading Accession and Version

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