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JAK1 Janus kinase 1 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110402219, updated on 11-Apr-2024

Summary

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Gene symbol
JAK1
Gene description
Janus kinase 1
See related
Ensembl:ENSNMEG00000009580
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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See JAK1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
25
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 7 NC_034415.1 (28424819..28477433, complement)

Chromosome 7 - NC_034415.1Genomic Context describing neighboring genes Neighboring gene cache domain containing 1 Neighboring gene ribonucleoprotein, PTB binding 2 Neighboring gene uncharacterized LOC110402221 Neighboring gene adenylate kinase 4 Neighboring gene DnaJ heat shock protein family (Hsp40) member C6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034415.1 Chromosome 7 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034415.1 Reference NumMel1.0 Primary Assembly

    Range
    28424819..28477433 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021404018.1 → XP_021259693.1  tyrosine-protein kinase JAK1

    Conserved Domains (5) summary
    cd05079
    Location:866 → 1149
    PTKc_Jak1_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 1
    smart00295
    Location:56 → 286
    B41; Band 4.1 homologues
    cd05077
    Location:578 → 842
    PTK_Jak1_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 1
    cl15255
    Location:422 → 522
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:282 → 422
    PH-like; Pleckstrin homology-like domain

  2. XM_021404016.1 → XP_021259691.1  tyrosine-protein kinase JAK1

    Related
    ENSNMEP00000010024.1, ENSNMET00000015865.1
    Conserved Domains (5) summary
    cd05079
    Location:866 → 1149
    PTKc_Jak1_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 1
    smart00295
    Location:56 → 286
    B41; Band 4.1 homologues
    cd05077
    Location:578 → 842
    PTK_Jak1_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 1
    cl15255
    Location:422 → 522
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:282 → 422
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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