Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

LOC110673971 - CYP11B2 promoter

This region represents the promoter of the cytochrome P450 family 11 subfamily B member 2 (CYP11B2) gene. Activity of this promoter is induced by angiotensin II and potassium and cyclic AMP through the association of nuclear receptor family members to multiple recognition sites in this sequence. Nuclear receptor subfamily 4 group A members 1 and 2 positively regulate promoter activity, which may be attenuated by nuclear receptor subfamily 5 group A member 1 (Nr5a1/Sf1). An Alu retroelement in the distal region may function as an enhancer of promoter activity. A naturally-occurring sequence polymorphism, rs1799998, affects a binding site for nuclear receptor family members, and was shown to be associated with hypertension. [provided by RefSeq, Jul 2017]

Genes similar to LOC110673971

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa