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LOC110673973 Cyp11b2 promoter [ Mus musculus (house mouse) ]

Gene ID: 110673973, updated on 9-Aug-2024

Summary

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Gene symbol
LOC110673973
Gene description
Cyp11b2 promoter
Gene type
biological region
Feature type(s)
protein_bind
regulatory: enhancer, promoter
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366803
Summary
This region represents the promoter of the cytochrome P450 family 11 subfamily B member 2 (Cyp11b2) gene. This promoter is induced by cyclic AMP and proopiomelanocortin, and contains a conserved binding site for nuclear receptor subfamily 5 group A member 1 (Nr5a1/Sf1). [provided by RefSeq, Jul 2017]
Orthologs
human all
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Genomic context

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See LOC110673973 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74728086..74728514)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74856237..74856665)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene glycosylphosphatidylinositol anchored molecule like 2 Neighboring gene cytochrome P450, family 11, subfamily b, polypeptide 1 Neighboring gene cytochrome P450, family 11, subfamily b, polypeptide 2 Neighboring gene predicted gene, 41347 Neighboring gene STARR-seq mESC enhancer starr_38998 Neighboring gene lymphocyte antigen 6 family member M Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:74736563-74736853 Neighboring gene predicted gene 6610

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aldosterone synthase gene regulation by angiotensin. Holland OB, et al. Endocr Res, 1995 Feb-May. PMID 7588410
  2. A cAMP-responsive element regulates expression of the mouse steroid 11 beta-hydroxylase gene. Rice DA, et al. J Biol Chem, 1989 Aug 25. PMID 2547779
  3. Adrenocortical-specific transgene expression directed by steroid hydroxylase gene promoters. Morley SD, et al. Endocr Res, 1996 Nov. PMID 8969922
  4. Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase. Mouw AR, et al. J Biol Chem, 1989 Jan 15. PMID 2783417
  5. A shared promoter element regulates the expression of three steroidogenic enzymes. Rice DA, et al. Mol Endocrinol, 1991 Oct. PMID 1775136

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Other Names

  • regulatory region 366803

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055455.1 

    Range
    101..529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    74728086..74728514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version