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BAZ2A bromodomain adjacent to zinc finger domain 2A [ Homo sapiens (human) ]

Gene ID: 11176, updated on 27-Nov-2024

Summary

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Official Symbol
BAZ2Aprovided by HGNC
Official Full Name
bromodomain adjacent to zinc finger domain 2Aprovided by HGNC
Primary source
HGNC:HGNC:962
See related
Ensembl:ENSG00000076108 MIM:605682; AllianceGenome:HGNC:962
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TIP5; WALp3
Summary
Enables histone binding activity. Contributes to RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA methylation-dependent heterochromatin formation; negative regulation of transcription by RNA polymerase I; and rDNA heterochromatin formation. Predicted to act upstream of or within heterochromatin formation. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis (RPKM 26.6), placenta (RPKM 20.1) and 25 other tissues See more
Orthologs
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Genomic context

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See BAZ2A in Genome Data Viewer
Location:
12q13.3
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (56595596..56638318, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (56563591..56604975, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (56989380..57030143, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, H/ACA box 105C Neighboring gene heat shock protein family D (Hsp60) member 1 pseudogene 4 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:56916039-56916782 Neighboring gene RNA binding motif single stranded interacting protein 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:56959127-56959665 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:56959666-56960203 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6503 Neighboring gene RNA, U6 small nuclear 343, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:57020987-57021488 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4561 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6504 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6505 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6506 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6507 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4562 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:57029126-57029638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6509 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:57030665-57031176 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:57038866-57039576 Neighboring gene ATP synthase F1 subunit beta Neighboring gene small nucleolar RNA, C/D box 59B Neighboring gene small nucleolar RNA, C/D box 59A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Pan-cancer and multi-omics analyses revealed the diagnostic and prognostic value of BAZ2A in liver cancer. Liu Y, et al. Sci Rep, 2024 Mar 4. PMID 38433277, Free PMC Article
  2. A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes. Anosova I, et al. Nucleic Acids Res, 2015 May 26. PMID 25916849, Free PMC Article
  3. Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC. Tallant C, et al. Structure, 2015 Jan 6. PMID 25533489, Free PMC Article
  4. BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence. Gu L, et al. Nat Genet, 2015 Jan. PMID 25485837
  5. lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs. Savić N, et al. Cell Stem Cell, 2014 Dec 4. PMID 25479748

See all (76) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pan-cancer and multi-omics analyses revealed the diagnostic and prognostic value of BAZ2A in liver cancer.
    Title: Pan-cancer and multi-omics analyses revealed the diagnostic and prognostic value of BAZ2A in liver cancer.
  2. Nasopharyngeal carcinoma derived exosomes regulate the proliferation and migration of nasopharyngeal carcinoma cells by mediating the miR-99a-5p BAZ2A axis.
    Title: Nasopharyngeal carcinoma derived exosomes regulate the proliferation and migration of nasopharyngeal carcinoma cells by mediating the miR-99a-5p BAZ2A axis.
  3. BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer.
    Title: BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer.
  4. BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.
    Title: BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.
  5. Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.
    Title: Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.
  6. the results of the present study demonstrated that TIP5 regulates beta-catenin/TCF7L2 signaling via TIP5 during HCC progression and suggests that TIP5 may be a promising therapeutic target for the treatment of HCC.
    Title: The transcription factor 7 like 2‑binding protein TIP5 activates β‑catenin/transcription factor signaling in hepatocellular carcinoma.
  7. Data suggest that binding of helical tail of histone 3 (H3) with PHD ('plant homeodomain') fingers of BAZ2A or BAZ2B (bromodomain adjacent to zinc finger domain 2A or 2B) requires molecular recognition of secondary structure motifs within H3 tail and could represent an additional layer of regulation in epigenetic processes.
    Title: Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.
  8. Data show that SUMOylated BANP, E5R, and Nac1 (BEN) domain 3 (BEND3) stabilizes NoRC component TTF-1-interacting protein 5 (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase
    Title: BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase.
  9. Crystal structures of PHD zinc finger and bromodomains from human TIP5 and BAZ2B in free form and bound to H3 and/or H4 histones.
    Title: Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
  10. The study showed that the NMR structure of the TAM domain of TIP5 resembles the fold of the MBD domain, found in methyl-CpG binding proteins.
    Title: A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
New gene functions in megakaryopoiesis and platelet formation.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of bromodomain adjacent to zinc finger domain protein 2A (BAZ2A) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ13768, FLJ13780, FLJ45876, KIAA0314, DKFZp781B109

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
contributes_to RNA polymerase I core promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables lysine-acetylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA methylation-dependent constitutive heterochromatin formation ISO
Inferred from Sequence Orthology
more info
  
involved_in DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in RNA polymerase I preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in heterochromatin formation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of transcription by RNA polymerase I ISO
Inferred from Sequence Orthology
more info
  
involved_in rDNA heterochromatin formation ISO
Inferred from Sequence Orthology
more info
  
involved_in rDNA heterochromatin formation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of NoRC complex ISO
Inferred from Sequence Orthology
more info
  
part_of chromatin silencing complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nuclear speck IDA
Inferred from Direct Assay
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleolus NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in rDNA heterochromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in rDNA heterochromatin ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
bromodomain adjacent to zinc finger domain protein 2A
Names
TTF-I interacting peptide 5
TTF-I-interacting protein 5
transcription termination factor I-interacting protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300905.2 → NP_001287834.1  bromodomain adjacent to zinc finger domain protein 2A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter, differs in the 5' UTR, and uses a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC090681, AK023842, DB215236
    Consensus CDS
    CCDS73483.1
    UniProtKB/TrEMBL
    F8VU39
    Related
    ENSP00000447941.1, ENST00000549884.6
    Conserved Domains (5) summary
    cd05503
    Location:1796 → 1892
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:846 → 911
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:549 → 621
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1676 → 1722
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:1437 → 1475
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

  2. NM_001351156.2 → NP_001338085.1  bromodomain adjacent to zinc finger domain protein 2A isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes isoform 3.
    Source sequence(s)
    AC090681
    Related
    ENSP00000368754.3, ENST00000379441.7
    Conserved Domains (7) summary
    cd05503
    Location:1766 → 1862
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:816 → 881
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:519 → 591
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1646 → 1692
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15613
    Location:1407 → 1441
    WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    cl26170
    Location:360 → 492
    DUF4115; Domain of unknown function (DUF4115)
    cl27975
    Location:1295 → 1398
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  3. NM_013449.4 → NP_038477.2  bromodomain adjacent to zinc finger domain protein 2A isoform 1

    See identical proteins and their annotated locations for NP_038477.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC090681, AK023842, CD686304, CR749379
    Consensus CDS
    CCDS44924.1
    UniProtKB/Swiss-Prot
    B3KN66, O00536, O15030, Q68DI8, Q96H26, Q9UIF9
    Related
    ENSP00000446880.1, ENST00000551812.5
    Conserved Domains (5) summary
    cd05503
    Location:1798 → 1894
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:848 → 913
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:551 → 623
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1678 → 1724
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:1439 → 1477
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    56595596..56638318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047428142.1 → XP_047284098.1  bromodomain adjacent to zinc finger domain protein 2A isoform X4

  2. XM_047428148.1 → XP_047284104.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  3. XM_047428155.1 → XP_047284111.1  bromodomain adjacent to zinc finger domain protein 2A isoform X12

  4. XM_047428151.1 → XP_047284107.1  bromodomain adjacent to zinc finger domain protein 2A isoform X9

  5. XM_047428145.1 → XP_047284101.1  bromodomain adjacent to zinc finger domain protein 2A isoform X7

  6. XM_047428166.1 → XP_047284122.1  bromodomain adjacent to zinc finger domain protein 2A isoform X18

  7. XM_047428144.1 → XP_047284100.1  bromodomain adjacent to zinc finger domain protein 2A isoform X6

  8. XM_047428141.1 → XP_047284097.1  bromodomain adjacent to zinc finger domain protein 2A isoform X3

  9. XM_047428139.1 → XP_047284095.1  bromodomain adjacent to zinc finger domain protein 2A isoform X1

  10. XM_047428147.1 → XP_047284103.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  11. XM_047428159.1 → XP_047284115.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  12. XM_047428157.1 → XP_047284113.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  13. XM_047428164.1 → XP_047284120.1  bromodomain adjacent to zinc finger domain protein 2A isoform X16

  14. XM_047428163.1 → XP_047284119.1  bromodomain adjacent to zinc finger domain protein 2A isoform X15

  15. XM_047428153.1 → XP_047284109.1  bromodomain adjacent to zinc finger domain protein 2A isoform X11

  16. XM_047428158.1 → XP_047284114.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  17. XM_047428149.1 → XP_047284105.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  18. XM_047428169.1 → XP_047284125.1  bromodomain adjacent to zinc finger domain protein 2A isoform X20

  19. XM_047428168.1 → XP_047284124.1  bromodomain adjacent to zinc finger domain protein 2A isoform X10

  20. XM_047428167.1 → XP_047284123.1  bromodomain adjacent to zinc finger domain protein 2A isoform X19

  21. XM_047428162.1 → XP_047284118.1  bromodomain adjacent to zinc finger domain protein 2A isoform X14

  22. XM_047428161.1 → XP_047284117.1  bromodomain adjacent to zinc finger domain protein 2A isoform X5

    UniProtKB/TrEMBL
    F8VU39

  23. XM_011537806.3 → XP_011536108.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

    See identical proteins and their annotated locations for XP_011536108.1

    Conserved Domains (5) summary
    cd05503
    Location:1803 → 1899
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:846 → 911
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:549 → 621
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1683 → 1729
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:1437 → 1475
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

  24. XM_017018741.2 → XP_016874230.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

    Conserved Domains (5) summary
    cd05503
    Location:1803 → 1899
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:846 → 911
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:549 → 621
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1683 → 1729
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:1437 → 1475
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

  25. XM_047428150.1 → XP_047284106.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  26. XM_047428165.1 → XP_047284121.1  bromodomain adjacent to zinc finger domain protein 2A isoform X17

  27. XM_047428156.1 → XP_047284112.1  bromodomain adjacent to zinc finger domain protein 2A isoform X13

  28. XM_047428154.1 → XP_047284110.1  bromodomain adjacent to zinc finger domain protein 2A isoform X11

  29. XM_047428146.1 → XP_047284102.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  30. XM_011537805.3 → XP_011536107.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

    See identical proteins and their annotated locations for XP_011536107.1

    Conserved Domains (5) summary
    cd05503
    Location:1803 → 1899
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:846 → 911
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:549 → 621
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1683 → 1729
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:1437 → 1475
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

  31. XM_047428160.1 → XP_047284116.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  32. XM_047428143.1 → XP_047284099.1  bromodomain adjacent to zinc finger domain protein 2A isoform X5

    UniProtKB/TrEMBL
    F8VU39

  33. XM_047428140.1 → XP_047284096.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  34. XM_047428152.1 → XP_047284108.1  bromodomain adjacent to zinc finger domain protein 2A isoform X10

  35. XM_011537809.3 → XP_011536111.1  bromodomain adjacent to zinc finger domain protein 2A isoform X21

    Conserved Domains (5) summary
    cd05503
    Location:1255 → 1351
    Bromo_BAZ2A_B_like; Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting ...
    smart00571
    Location:298 → 363
    DDT; domain in different transcription and chromosome remodeling factors
    cd01397
    Location:10 → 73
    HAT_MBD; Methyl-CpG binding domains (MBD) present in putative chromatin remodelling factor such as BAZ2A; BAZ2A contains a MBD, DDT, PHD-type zinc finger and Bromo domain suggesting that BAZ2A might be associated with histone acetyltransferase (HAT) activity. The ...
    cd15629
    Location:1135 → 1181
    PHD_BAZ2A; PHD finger found in bromodomain adjacent to zinc finger domain protein 2A (BAZ2A)
    pfam15614
    Location:889 → 927
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

  36. XM_047428170.1 → XP_047284126.1  bromodomain adjacent to zinc finger domain protein 2A isoform X22

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    56563591..56604975 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054370868.1 → XP_054226843.1  bromodomain adjacent to zinc finger domain protein 2A isoform X4

  2. XM_054370870.1 → XP_054226845.1  bromodomain adjacent to zinc finger domain protein 2A isoform X6

  3. XM_054370879.1 → XP_054226854.1  bromodomain adjacent to zinc finger domain protein 2A isoform X27

  4. XM_054370875.1 → XP_054226850.1  bromodomain adjacent to zinc finger domain protein 2A isoform X26

    UniProtKB/TrEMBL
    J3KPG5

  5. XM_054370871.1 → XP_054226846.1  bromodomain adjacent to zinc finger domain protein 2A isoform X25

  6. XM_054370894.1 → XP_054226869.1  bromodomain adjacent to zinc finger domain protein 2A isoform X28

  7. XM_054370867.1 → XP_054226842.1  bromodomain adjacent to zinc finger domain protein 2A isoform X24

  8. XM_054370865.1 → XP_054226840.1  bromodomain adjacent to zinc finger domain protein 2A isoform X23

  9. XM_054370886.1 → XP_054226861.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  10. XM_054370883.1 → XP_054226858.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  11. XM_054370892.1 → XP_054226867.1  bromodomain adjacent to zinc finger domain protein 2A isoform X16

  12. XM_054370891.1 → XP_054226866.1  bromodomain adjacent to zinc finger domain protein 2A isoform X15

  13. XM_054370880.1 → XP_054226855.1  bromodomain adjacent to zinc finger domain protein 2A isoform X13

  14. XM_054370877.1 → XP_054226852.1  bromodomain adjacent to zinc finger domain protein 2A isoform X11

  15. XM_054370872.1 → XP_054226847.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  16. XM_054370884.1 → XP_054226859.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  17. XM_054370874.1 → XP_054226849.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  18. XM_054370889.1 → XP_054226864.1  bromodomain adjacent to zinc finger domain protein 2A isoform X5

    UniProtKB/TrEMBL
    F8VU39

  19. XM_054370890.1 → XP_054226865.1  bromodomain adjacent to zinc finger domain protein 2A isoform X14

  20. XM_054370882.1 → XP_054226857.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  21. XM_054370896.1 → XP_054226871.1  bromodomain adjacent to zinc finger domain protein 2A isoform X10

  22. XM_054370897.1 → XP_054226872.1  bromodomain adjacent to zinc finger domain protein 2A isoform X20

  23. XM_054370895.1 → XP_054226870.1  bromodomain adjacent to zinc finger domain protein 2A isoform X19

  24. XM_054370885.1 → XP_054226860.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  25. XM_054370893.1 → XP_054226868.1  bromodomain adjacent to zinc finger domain protein 2A isoform X17

  26. XM_054370881.1 → XP_054226856.1  bromodomain adjacent to zinc finger domain protein 2A isoform X13

  27. XM_054370878.1 → XP_054226853.1  bromodomain adjacent to zinc finger domain protein 2A isoform X11

  28. XM_054370873.1 → XP_054226848.1  bromodomain adjacent to zinc finger domain protein 2A isoform X8

  29. XM_054370887.1 → XP_054226862.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  30. XM_054370888.1 → XP_054226863.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  31. XM_054370869.1 → XP_054226844.1  bromodomain adjacent to zinc finger domain protein 2A isoform X5

    UniProtKB/TrEMBL
    F8VU39

  32. XM_054370866.1 → XP_054226841.1  bromodomain adjacent to zinc finger domain protein 2A isoform X2

  33. XM_054370876.1 → XP_054226851.1  bromodomain adjacent to zinc finger domain protein 2A isoform X10

  34. XM_054370898.1 → XP_054226873.1  bromodomain adjacent to zinc finger domain protein 2A isoform X21

  35. XM_054370899.1 → XP_054226874.1  bromodomain adjacent to zinc finger domain protein 2A isoform X22

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9UIF9.4 GenPept UniProtKB/Swiss-Prot:Q9UIF9

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