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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001205049.2 → NP_001191978.1 acrosin isoform 2 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC122401
- UniProtKB/TrEMBL
-
Q3ZB04
- Conserved Domains (2) summary
-
- smart00020
Location:42 → 238
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:43 → 238
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_001277245.2 → NP_001264174.1 acrosin isoform 3
See identical proteins and their annotated locations for NP_001264174.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 5' end, which results in the use of a downstream AUG translation initiation site, compared to variant 1. It encodes isoform 3, which is shorter at the N-terminus, compared to isoform 1. Variants 3, 4 and 7 encode the same isoform (3).
- Source sequence(s)
-
AC122401
- UniProtKB/TrEMBL
- Q3ZB05, Q3ZB06
- Conserved Domains (1) summary
-
- smart00020
Location:1 → 230
- Tryp_SPc; Trypsin-like serine protease
-
NM_001277246.2 → NP_001264175.1 acrosin isoform 3
See identical proteins and their annotated locations for NP_001264175.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) uses an alternate splice site in the 5' end, which results in the use of a downstream AUG translation initiation site, compared to variant 1. It encodes isoform 3, which is shorter at the N-terminus, compared to isoform 1. Variants 3, 4 and 7 encode the same isoform (3).
- Source sequence(s)
-
AC122401
- UniProtKB/TrEMBL
- Q3ZB05, Q3ZB06
- Conserved Domains (1) summary
-
- smart00020
Location:1 → 230
- Tryp_SPc; Trypsin-like serine protease
-
NM_001277247.2 → NP_001264176.1 acrosin isoform 4 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.
- Source sequence(s)
-
AC122401
- UniProtKB/TrEMBL
-
Q3ZB06
- Conserved Domains (2) summary
-
- smart00020
Location:27 → 244
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:26 → 247
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_001411168.1 → NP_001398097.1 acrosin isoform 5 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 5, which has a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC122401
- Related
- ENSMUSP00000155369.2, ENSMUST00000230978.2
-
NM_001411169.1 → NP_001398098.1 acrosin isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (7) uses an alternate splice site in the 5' end, which results in the use of a downstream AUG translation initiation site, compared to variant 1. It encodes isoform 3, which is shorter at the N-terminus, compared to isoform 1. Variants 3, 4 and 7 encode the same isoform (3).
- Source sequence(s)
-
AC122401
- UniProtKB/TrEMBL
-
Q3ZB05
-
NM_013455.4 → NP_038483.1 acrosin isoform 1 precursor
See identical proteins and their annotated locations for NP_038483.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC122401
- Consensus CDS
-
CCDS27755.1
- UniProtKB/Swiss-Prot
-
P23578
- UniProtKB/TrEMBL
-
Q3ZB06
- Related
- ENSMUSP00000023295.3, ENSMUST00000023295.3
- Conserved Domains (2) summary
-
- smart00020
Location:42 → 286
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:43 → 289
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000081.7 Reference GRCm39 C57BL/6J
- Range
-
89452549..89458790
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001277248.1: Suppressed sequence
- Description
- NM_001277248.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.