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Mir203b microRNA 203b [ Mus musculus (house mouse) ]

Gene ID: 114483633, updated on 17-Aug-2024

Summary

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Official Symbol
Mir203bprovided by MGI
Official Full Name
microRNA 203bprovided by MGI
Primary source
MGI:MGI:6364977
See related
miRBase:MI0040622; AllianceGenome:MGI:6364977
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm51289; mmu-mir-203b
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See Mir203b in Genome Data Viewer
Location:
12; 12 F1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112097321..112097380, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112130887..112130946, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene tudor domain containing 9 Neighboring gene predicted gene, 46381 Neighboring gene microRNA 3073a Neighboring gene microRNA 3073b Neighboring gene asparaginase Neighboring gene microRNA 203 Neighboring gene kinesin family member 26A Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the transcription factor, AFF4, as a new target of miR-203 in CNS. Li S, et al. Int J Biol Macromol, 2021 Jun 30. PMID 33878354
  2. Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation. Warnefors M, et al. Genome Res, 2017 Dec. PMID 29079676, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of the transcription factor, AFF4, as a new target of miR-203 in CNS.
    Title: Identification of the transcription factor, AFF4, as a new target of miR-203 in CNS.
Submit: New GeneRIF Correction

General gene information

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Other Names

  • microRNA mir-203b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_162782.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC112520

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    112097321..112097380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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