Ly6g5c lymphocyte antigen 6 family member G5C [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ly6g5cprovided by MGI
Official Full Name: lymphocyte antigen 6 family member G5Cprovided by MGI
Primary source: MGI:MGI:2148974
See related: Ensembl:ENSMUSG00000034482 AllianceGenome:MGI:2148974
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: G5c; NG33
Summary: Enables identical protein binding activity. Part of protein-containing complex. Colocalizes with external side of plasma membrane. Is expressed in brain and embryo. Orthologous to human LY6G5C (lymphocyte antigen 6 family member G5C). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Restricted expression toward genital fat pad adult (RPKM 932.2) See more
Orthologs: human all
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Genomic context

Location:: 17 B1; 17 18.59 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (35327270..35331149)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (35108294..35112173)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice.
Title: CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Gene trapped (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:490525

Ly6g5c (e-PCR), detects polymorphism
- UniSTS:256868

Ly6g5c (e-PCR), detects polymorphism
- UniSTS:256869

NoName (e-PCR)
- UniSTS:493019

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	IDA Inferred from Direct Assay more info	PubMed
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
colocalizes_with external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
colocalizes_with external side of plasma membrane	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with external side of plasma membrane	ISO Inferred from Sequence Orthology more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	IDA Inferred from Direct Assay more info	PubMed
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: lymphocyte antigen 6 complex locus protein G5c

Names: lymphocyte antigen 6 complex, locus G5C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.