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mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [ Sparus aurata (gilthead seabream) ]

Gene ID: 115574486, updated on 17-Mar-2024

Summary

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Gene symbol
mthfd1l
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
See related
Ensembl:ENSSAUG00010011834
Gene type
protein coding
RefSeq status
MODEL
Organism
Sparus aurata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Spariformes; Sparidae; Sparus
Orthologs
human zebrafish all
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Genomic context

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See mthfd1l in Genome Data Viewer
Location:
chromosome: 22
Exon count:
28
Annotation release Status Assembly Chr Location
100 current fSpaAur1.1 (GCF_900880675.1) 22 NC_044208.1 (18433185..18470813, complement)

Chromosome 22 - NC_044208.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 2b Neighboring gene A kinase (PRKA) anchor protein 12b Neighboring gene syntaxin-11-like Neighboring gene syntaxin 11b, tandem duplicate 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044208.1 Chromosome 22 Reference fSpaAur1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables formate-tetrahydrofolate ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
monofunctional C1-tetrahydrofolate synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sparus aurata Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSpaAur1.1 Primary Assembly

Genomic

  1. NC_044208.1 Reference fSpaAur1.1 Primary Assembly

    Range
    18433185..18470813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030406052.1 → XP_030261912.1  monofunctional C1-tetrahydrofolate synthase, mitochondrial

    UniProtKB/TrEMBL
    A0A671WI27, A0A671WPN4
    Conserved Domains (3) summary
    PLN02759
    Location:347 → 974
    PLN02759; Formate--tetrahydrofolate ligase
    COG0190
    Location:79 → 292
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    cl21454
    Location:196 → 330
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_030406051.1 → XP_030261911.1  monofunctional C1-tetrahydrofolate synthase, mitochondrial

    UniProtKB/TrEMBL
    A0A671WI27, A0A671WPN4
    Related
    ENSSAUP00010038576.1, ENSSAUT00010040663.1
    Conserved Domains (3) summary
    PLN02759
    Location:347 → 974
    PLN02759; Formate--tetrahydrofolate ligase
    COG0190
    Location:79 → 292
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    cl21454
    Location:196 → 330
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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