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arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 [ Etheostoma spectabile (orangethroat darter) ]

Gene ID: 116707468, updated on 18-Mar-2024

Summary

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Gene symbol
arhgef11
Gene description
Rho guanine nucleotide exchange factor (GEF) 11
Locus tag
FQN60_006298
Gene type
protein coding
RefSeq status
MODEL
Organism
Etheostoma spectabile
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma
Orthologs
human zebrafish all
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Genomic context

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See arhgef11 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
42
Annotation release Status Assembly Chr Location
100 current UIUC_Espe_1.0 (GCF_008692095.1) 19 NC_045751.1 (7669740..7693428, complement)

Chromosome 19 - NC_045751.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116669361 Neighboring gene vang-like protein 2 Neighboring gene myeloid-associated differentiation marker homolog Neighboring gene uncharacterized LOC116669456

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045751.1 Chromosome 19 Reference UIUC_Espe_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 11
Names
Rho guanine nucleotide exchange factor 11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Etheostoma spectabile Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UIUC_Espe_1.0 Primary Assembly

Genomic

  1. NC_045751.1 Reference UIUC_Espe_1.0 Primary Assembly

    Range
    7669740..7693428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032544812.1 → XP_032400703.1  rho guanine nucleotide exchange factor 11 isoform X4

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:743 → 924
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:47 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:303 → 449
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:941 → 1075
    PH-like; Pleckstrin homology-like domain

  2. XM_032544811.1 → XP_032400702.1  rho guanine nucleotide exchange factor 11 isoform X3

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:745 → 926
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:305 → 451
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:943 → 1077
    PH-like; Pleckstrin homology-like domain

  3. XM_032544810.1 → XP_032400701.1  rho guanine nucleotide exchange factor 11 isoform X2

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:748 → 929
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:52 → 126
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:308 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:946 → 1080
    PH-like; Pleckstrin homology-like domain

  4. XM_032544815.1 → XP_032400706.1  rho guanine nucleotide exchange factor 11 isoform X7

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:719 → 900
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:54 → 128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:279 → 425
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:917 → 1051
    PH-like; Pleckstrin homology-like domain

  5. XM_032544813.1 → XP_032400704.1  rho guanine nucleotide exchange factor 11 isoform X5

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:740 → 921
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:54 → 128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:310 → 456
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:938 → 1072
    PH-like; Pleckstrin homology-like domain

  6. XM_032544814.1 → XP_032400705.1  rho guanine nucleotide exchange factor 11 isoform X6

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:734 → 915
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:54 → 128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:310 → 456
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:932 → 1066
    PH-like; Pleckstrin homology-like domain

  7. XM_032544816.1 → XP_032400707.1  rho guanine nucleotide exchange factor 11 isoform X8

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:750 → 931
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:54 → 128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:310 → 456
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:948 → 1082
    PH-like; Pleckstrin homology-like domain

  8. XM_032544809.1 → XP_032400700.1  rho guanine nucleotide exchange factor 11 isoform X1

    UniProtKB/TrEMBL
    A0A5J5CLM9
    Conserved Domains (4) summary
    smart00325
    Location:750 → 931
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:54 → 128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02565
    Location:310 → 456
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:948 → 1082
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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