U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rhbdl1 rhomboid like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 117025, updated on 2-Nov-2024

Summary

Official Symbol
Rhbdl1provided by RGD
Official Full Name
rhomboid like 1provided by RGD
Primary source
RGD:620699
See related
EnsemblRapid:ENSRNOG00000019921 AllianceGenome:RGD:620699
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rhbdl
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Orthologous to human RHBDL1 (rhomboid like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 44.0), Adrenal (RPKM 14.3) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rhbdl1 in Genome Data Viewer
Location:
10q12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15359027..15362530, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14854514..14858848, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15201503..15205856, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 24 Neighboring gene jumonji domain containing 8 Neighboring gene STIP1 homology and U-box containing protein 1 Neighboring gene ras homolog family member T2 Neighboring gene WD repeat domain 90 Neighboring gene MAPK regulated co-repressor interacting protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
rhomboid-related protein 1
Names
RRP
rhomboid protease 1
rhomboid, veinlet-like 1
rhomboid-like protein 1
NP_001178751.1
XP_006245956.1
XP_008765759.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191822.1NP_001178751.1  rhomboid-related protein 1

    See identical proteins and their annotated locations for NP_001178751.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HD64, G3V8M7
    Related
    ENSRNOP00000026971.5, ENSRNOT00000026971.7
    Conserved Domains (1) summary
    pfam01694
    Location:174328
    Rhomboid; Rhomboid family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15359027..15362530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006245894.5XP_006245956.1  rhomboid-related protein 1 isoform X2

    UniProtKB/TrEMBL
    G3V8M7
    Conserved Domains (1) summary
    pfam01694
    Location:176330
    Rhomboid; Rhomboid family
  2. XM_008767537.4XP_008765759.1  rhomboid-related protein 1 isoform X1

    UniProtKB/TrEMBL
    G3V8M7
    Conserved Domains (1) summary
    pfam01694
    Location:234388
    Rhomboid; Rhomboid family