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Ank1 ankyrin 1, erythroid [ Mus musculus (house mouse) ]

Gene ID: 11733, updated on 27-Nov-2024

Summary

Official Symbol
Ank1provided by MGI
Official Full Name
ankyrin 1, erythroidprovided by MGI
Primary source
MGI:MGI:88024
See related
Ensembl:ENSMUSG00000031543 AllianceGenome:MGI:88024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
nb; pale; Ank-1
Summary
Predicted to enable several functions, including enzyme binding activity; spectrin binding activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including erythrocyte development; multicellular organismal-level iron ion homeostasis; and porphyrin-containing compound biosynthetic process. Located in cortical cytoskeleton; membrane; and spectrin-associated cytoskeleton. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; retina; and skeletal muscle. Used to study hereditary spherocytosis type 1 and malaria. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in cerebellum adult (RPKM 21.2), liver E14.5 (RPKM 20.5) and 15 other tissues See more
Orthologs
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Genomic context

See Ank1 in Genome Data Viewer
Location:
8 A2; 8 11.42 cM
Exon count:
50
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (23464852..23640517)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22974836..23150501)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene K(lysine) acetyltransferase 6A Neighboring gene mitochondrial ribosomal protein L4 pseudogene Neighboring gene LSM6 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene predicted gene 15816 Neighboring gene STARR-seq mESC enhancer starr_20914 Neighboring gene microRNA 3107 Neighboring gene microRNA 486 Neighboring gene NK6 homeobox 3 Neighboring gene predicted gene, 30306 Neighboring gene predicted gene, 30247

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
 
enables cytoskeletal anchor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cytoskeletal anchor activity ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables spectrin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables spectrin binding ISO
Inferred from Sequence Orthology
more info
 
enables transmembrane transporter binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in A band ISO
Inferred from Sequence Orthology
more info
 
located_in M band ISO
Inferred from Sequence Orthology
more info
 
located_in Z disc ISO
Inferred from Sequence Orthology
more info
 
part_of ankyrin-1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of ankyrin-1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in axolemma ISO
Inferred from Sequence Orthology
more info
 
located_in cortical cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
located_in sarcolemma ISO
Inferred from Sequence Orthology
more info
 
located_in sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in spectrin-associated cytoskeleton IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in spectrin-associated cytoskeleton ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ankyrin-1
Names
erythrocyte ankyrin
normoblastic anemia

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110783.3NP_001104253.1  ankyrin-1 isoform 1

    See identical proteins and their annotated locations for NP_001104253.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AI846810, AK147278, AK147483, AK158131, CJ105945
    Consensus CDS
    CCDS52523.1
    UniProtKB/TrEMBL
    A0A0R4J1N7
    Related
    ENSMUSP00000113571.3, ENSMUST00000121802.9
    Conserved Domains (8) summary
    smart00218
    Location:9521056
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:374583
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:365490
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:14421525
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:342433
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:4798
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:753807
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:700731
    ANK; ANK repeat [structural motif]
  2. NM_001277280.2NP_001264209.1  ankyrin-1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice junction in a 3' exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but lacks two alternate internal segments compared to isoform 1.
    Source sequence(s)
    AC126445, AI846810, AK147483, AK158131, CJ105945
    Consensus CDS
    CCDS72099.1
    UniProtKB/Swiss-Prot
    Q02357
    Related
    ENSMUSP00000106316.3, ENSMUST00000110688.9
    Conserved Domains (8) summary
    smart00218
    Location:9441048
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:374583
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:365490
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:14341517
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:342433
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:4798
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:753807
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:700731
    ANK; ANK repeat [structural motif]
  3. NM_001277281.2NP_001264210.1  ankyrin-1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame exon compared to variant 1. The encoded isoform (4) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AC126445, AI846810, AK147483, CJ101195, M84756
    Consensus CDS
    CCDS72100.1
    UniProtKB/TrEMBL
    E9QNT8
    Related
    ENSMUSP00000113531.2, ENSMUST00000117662.8
    Conserved Domains (8) summary
    smart00218
    Location:9071011
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:337546
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:328453
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:13971480
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:305396
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:1061
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:716770
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:663694
    ANK; ANK repeat [structural motif]
  4. NM_001277284.2NP_001264213.1  ankyrin-1 isoform 5

    See identical proteins and their annotated locations for NP_001264213.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has an alternate 5' exon, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction in a 3' exon compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus, lacks an alternate internal segment, and contains an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AC126445, AI846810, AK147483, BC079910, CJ101195
    Consensus CDS
    CCDS72101.1
    UniProtKB/TrEMBL
    Q0VGY9
    Related
    ENSMUSP00000113656.2, ENSMUST00000117296.8
    Conserved Domains (8) summary
    smart00218
    Location:9071011
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:337546
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:328453
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:13971480
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:305396
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:1061
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:716770
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:663694
    ANK; ANK repeat [structural motif]
  5. NM_001277286.2NP_001264215.1  ankyrin-1 isoform 6

    See identical proteins and their annotated locations for NP_001264215.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame segment compared to variant 1. The encoded isoform (6) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AI846810, AK147483, AK147597, X69063
    Consensus CDS
    CCDS72102.1
    UniProtKB/TrEMBL
    B7ZW98
    Related
    ENSMUSP00000133322.2, ENSMUST00000173248.8
    Conserved Domains (8) summary
    smart00218
    Location:9231027
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:345554
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:336461
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:14131496
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:313404
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:1869
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:724778
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:671702
    ANK; ANK repeat [structural motif]
  6. NM_001277289.2NP_001264218.1  ankyrin-1 isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, represents use of an alternate promoter compared and initiates translation at an alternate start codon to variant 1. The encoded isoform (7) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC126445, AI846810, AK147483, AK147597, X69063
    Consensus CDS
    CCDS72103.1
    UniProtKB/TrEMBL
    D3YTV8
    Related
    ENSMUSP00000112850.2, ENSMUST00000118733.8
    Conserved Domains (8) summary
    smart00218
    Location:9231027
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:345554
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:336461
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:14131496
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:313404
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:1869
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:724778
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:671702
    ANK; ANK repeat [structural motif]
  7. NM_001310436.1NP_001297365.1  ankyrin-1 isoform 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) has multiple differences compared to variant 1. These differences result in a distinct 5' UTR, translation initiation at an alternate start codon, and a novel 3' coding region. The encoded isoform (8) is shorter than and has distinct N- and C-termini compared to isoform 1.
    Source sequence(s)
    AI846810, AK134267, AK147483, BC079910, U73972
    Consensus CDS
    CCDS80865.1
    UniProtKB/Swiss-Prot
    Q02357
    UniProtKB/TrEMBL
    Q0VGY9
    Related
    ENSMUSP00000033947.9, ENSMUST00000033947.15
  8. NM_001310437.1NP_001297366.1  ankyrin-1 isoform 9

    See identical proteins and their annotated locations for NP_001297366.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon compared to variant 1. It encodes isoform 9, which has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AI846810, AK147483, U73972
    Consensus CDS
    CCDS80864.1
    UniProtKB/Swiss-Prot
    Q02357
    Related
    ENSMUSP00000112966.2, ENSMUST00000121075.8
  9. NM_031158.4NP_112435.2  ankyrin-1 isoform 2

    See identical proteins and their annotated locations for NP_112435.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame segment compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AI846810, AK147278, AK147483, X69063
    Consensus CDS
    CCDS22187.1
    UniProtKB/TrEMBL
    G5E8J2
    Related
    ENSMUSP00000081051.5, ENSMUST00000084038.11
    Conserved Domains (8) summary
    smart00218
    Location:9231027
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:345554
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:336461
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08805
    Location:14131496
    Death_ank1; Death domain of Ankyrin-1
    pfam12796
    Location:313404
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:1869
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:724778
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:671702
    ANK; ANK repeat [structural motif]

RNA

  1. NR_102385.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, represents use of an alternate promoter, and has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI846810, AK147483, AK147597, X69063
    Related
    ENSMUST00000173573.8
  2. NR_102386.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR, represents use of an alternate promoter, and has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI846810, AK147483, X69063
    Related
    ENSMUST00000123418.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    23464852..23640517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508990.2XP_006509053.1  ankyrin-1 isoform X2

    Conserved Domains (9) summary
    smart00218
    Location:9521056
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:415625
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:123468
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14421525
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:700731
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:49140
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:767819
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12771406
    UPA_2; UPA domain
    cl39094
    Location:579792
    Ank_2; Ankyrin repeats (3 copies)
  2. XM_006509000.2XP_006509063.1  ankyrin-1 isoform X12

    UniProtKB/TrEMBL
    D3Z5M4
    Related
    ENSMUSP00000113495.3, ENSMUST00000117270.9
    Conserved Domains (9) summary
    smart00218
    Location:9521056
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:415625
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:123468
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14421525
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:700731
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:49140
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:767819
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12771406
    UPA_2; UPA domain
    cl39094
    Location:579792
    Ank_2; Ankyrin repeats (3 copies)
  3. XM_006508989.4XP_006509052.1  ankyrin-1 isoform X1

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  4. XM_006508991.5XP_006509054.1  ankyrin-1 isoform X3

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  5. XM_006508992.5XP_006509055.1  ankyrin-1 isoform X4

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  6. XM_006508997.5XP_006509060.1  ankyrin-1 isoform X9

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  7. XM_006508993.5XP_006509056.1  ankyrin-1 isoform X5

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  8. XM_030243250.2XP_030099110.1  ankyrin-1 isoform X13

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  9. XM_006508994.5XP_006509057.1  ankyrin-1 isoform X6

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  10. XM_006508998.5XP_006509061.1  ankyrin-1 isoform X10

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  11. XM_006509001.5XP_006509064.1  ankyrin-1 isoform X14

    Conserved Domains (9) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14601543
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12951424
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  12. XM_006508995.5XP_006509058.1  ankyrin-1 isoform X7

    Related
    ENSMUSP00000117966.3, ENSMUST00000141784.9
    Conserved Domains (9) summary
    smart00218
    Location:9621066
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14521535
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12871416
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  13. XM_006508999.5XP_006509062.1  ankyrin-1 isoform X11

    Conserved Domains (9) summary
    smart00218
    Location:9621066
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14521535
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12871416
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  14. XM_006509002.5XP_006509065.1  ankyrin-1 isoform X15

    Conserved Domains (9) summary
    smart00218
    Location:9621066
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14521535
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12871416
    UPA_2; UPA domain
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  15. XM_006509003.5XP_006509066.1  ankyrin-1 isoform X16

    Conserved Domains (7) summary
    smart00218
    Location:9701074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:433643
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:141486
    PHA02876; ankyrin repeat protein; Provisional
    sd00045
    Location:718749
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:67158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:785837
    Ank_4; Ankyrin repeats (many copies)
    cl39094
    Location:597810
    Ank_2; Ankyrin repeats (3 copies)
  16. XM_006508996.3XP_006509059.1  ankyrin-1 isoform X8

    Conserved Domains (9) summary
    smart00218
    Location:9231027
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02875
    Location:386596
    PHA02875; ankyrin repeat protein; Provisional
    PHA02876
    Location:94439
    PHA02876; ankyrin repeat protein; Provisional
    cd08805
    Location:14131496
    Death_ank1; Death domain of Ankyrin-1
    sd00045
    Location:671702
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:20111
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:738790
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:12481377
    UPA_2; UPA domain
    cl39094
    Location:550763
    Ank_2; Ankyrin repeats (3 copies)
  17. XM_036153729.1XP_036009622.1  ankyrin-1 isoform X17

RNA

  1. XR_378776.5 RNA Sequence