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Gr22b Gustatory receptor 22b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 117492, updated on 9-Dec-2024

Summary

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Official Symbol
Gr22bprovided by FlyBase
Official Full Name
Gustatory receptor 22bprovided by FlyBase
Primary source
FLYBASE:FBgn0045500
Locus tag
Dmel_CG31931
See related
AllianceGenome:FB:FBgn0045500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG31931; CR31931; Dmel\CG31931; GR22b; Gr22bP; Gr2940.4
Summary
Predicted to enable ligand-gated monoatomic ion channel activity and sweet taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of taste and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in several cellular components, including axon; dendrite; and neuronal cell body. Is expressed in several structures, including adult labellum sensillum; labellum; larval gnathal ganglion; larval pharyngeal gustatory receptor neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Gr22b in Genome Data Viewer
Location:
22B2-22B2; 2-3 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1792057..1793268, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1792057..1793268, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 22d Neighboring gene Gustatory receptor 22c Neighboring gene Gustatory receptor 22a Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Soft Selective Sweep on Chemosensory Genes Correlates with Ancestral Preference for Toxic Noni in a Specialist Drosophila Population. Ferreira EA, et al. Genes (Basel), 2020 Dec 29. PMID 33383708, Free PMC Article
  2. Bitter taste receptors confer diverse functions to neurons. Delventhal R, et al. Elife, 2016 Feb 15. PMID 26880560, Free PMC Article
  3. Taste perception and coding in Drosophila. Thorne N, et al. Curr Biol, 2004 Jun 22. PMID 15202999
  4. Function and expression of the Drosophila gr genes in the perception of sweet, bitter and pheromone compounds. Thorne N, et al. Chem Senses, 2005 Jan. PMID 15738152
  5. Taste and pheromone perception in mammals and flies. Matsunami H, et al. Genome Biol, 2003. PMID 12844351, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sweet taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taste receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of taste ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in monoatomic ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
gustatory receptor 22b
Names
CG31931-PA
Gr22b-PA
gustatory receptor 2940.4
NP_001014456.1
  • point mutation, may be evolving pseudogene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1792057..1793268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014456.1 → NP_001014456.1  gustatory receptor 22b [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014456.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P84180, Q59E12
    Conserved Domains (1) summary
    pfam08395
    Location:17 → 385
    7tm_7; 7tm Chemosensory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P84180.1 P84180

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