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Sec22a SEC22 homolog A, vesicle trafficking protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 117513, updated on 4-Jan-2025

Summary

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Official Symbol
Sec22aprovided by RGD
Official Full Name
SEC22 homolog A, vesicle trafficking proteinprovided by RGD
Primary source
RGD:621659
See related
EnsemblRapid:ENSRNOG00000043069 AllianceGenome:RGD:621659
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sec22l2
Summary
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SEC22A (SEC22 homolog A, vesicle trafficking protein). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 123.3), Liver (RPKM 79.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Sec22a in Genome Data Viewer
Location:
11q22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78907552..78967575)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (65402583..65462329)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (68633080..68686553)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase family A, member 5 Neighboring gene uncharacterized LOC120095661 Neighboring gene uncharacterized LOC120095660 Neighboring gene uncharacterized LOC102551038 Neighboring gene adenylate cyclase 5 Neighboring gene uncharacterized LOC134481009

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus. Hay JC, et al. J Biol Chem, 1996 Mar 8. PMID 8621431
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vesicle-trafficking protein SEC22a
Names
SEC22 vesicle trafficking protein homolog A
SEC22 vesicle-trafficking protein-like 2
rSec22a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_057147.2 → NP_476488.2  vesicle-trafficking protein SEC22a

    See identical proteins and their annotated locations for NP_476488.2

    Status: PROVISIONAL

    Source sequence(s)
    BC081746
    UniProtKB/Swiss-Prot
    Q62891, Q642F4
    UniProtKB/TrEMBL
    A0A8I6G2P2, A6IRG9
    Related
    ENSRNOP00000061258.2, ENSRNOT00000063795.4
    Conserved Domains (1) summary
    cd14824
    Location:5 → 126
    Longin; longin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    78907552..78967575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008768693.4 → XP_008766915.3  vesicle-trafficking protein SEC22a isoform X1

    Related
    ENSRNOP00000104395.1, ENSRNOT00000166378.1

  2. XM_039087918.2 → XP_038943846.1  vesicle-trafficking protein SEC22a isoform X2

    Conserved Domains (1) summary
    cd14824
    Location:1 → 56
    Longin; longin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q642F4.1 GenPept UniProtKB/Swiss-Prot:Q642F4

Gene LinkOut

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