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LCK LCK proto-oncogene, Src family tyrosine kinase [ Mauremys mutica (yellowpond turtle) ]

Gene ID: 123355513, updated on 11-Apr-2024

Summary

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Gene symbol
LCK
Gene description
LCK proto-oncogene, Src family tyrosine kinase
Locus tag
KIL84_021653
Gene type
protein coding
RefSeq status
MODEL
Organism
Mauremys mutica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
Orthologs
human mouse all
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Genomic context

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See LCK in Genome Data Viewer
Location:
chromosome: 23
Exon count:
14
Annotation release Status Assembly Chr Location
100 current ASM2049712v1 (GCF_020497125.1) 23 NC_059094.1 (15104161..15136910)

Chromosome 23 - NC_059094.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit I Neighboring gene myotubularin-related protein 9-like Neighboring gene family with sequence similarity 167 member B Neighboring gene uncharacterized LOC123355514 Neighboring gene histone deacetylase 1 Neighboring gene MARCKS like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_059094.1 Chromosome 23 Reference ASM2049712v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in T cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Lck

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mauremys mutica Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2049712v1 Primary Assembly

Genomic

  1. NC_059094.1 Reference ASM2049712v1 Primary Assembly

    Range
    15104161..15136910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044998076.1 → XP_044854011.1  tyrosine-protein kinase Lck

    Conserved Domains (3) summary
    cd10362
    Location:122 → 222
    SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
    cd05067
    Location:236 → 499
    PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
    cl17036
    Location:64 → 117
    SH3; Src Homology 3 domain superfamily

  2. XM_044998075.1 → XP_044854010.1  tyrosine-protein kinase Lck

    Conserved Domains (3) summary
    cd10362
    Location:122 → 222
    SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
    cd05067
    Location:236 → 499
    PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
    cl17036
    Location:64 → 117
    SH3; Src Homology 3 domain superfamily

  3. XM_044998074.1 → XP_044854009.1  tyrosine-protein kinase Lck

    Conserved Domains (3) summary
    cd10362
    Location:122 → 222
    SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
    cd05067
    Location:236 → 499
    PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
    cl17036
    Location:64 → 117
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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