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LOC127270456 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:155098207-155099046 [ Homo sapiens (human) ]

Gene ID: 127270456, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127270456
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:155098207-155099046
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127270456 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (155125731..155126570)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (154265079..154265918)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (155098207..155099046)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene DCST1 antisense RNA 1 Neighboring gene ADAM15-EFNA4 readthrough Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1385 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1386 Neighboring gene NANOG hESC enhancer GRCh37_chr1:155037167-155037668 Neighboring gene EFNA4-EFNA3 readthrough Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:155041991-155042503 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:155043017-155043529 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1803 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:155044044-155044556 Neighboring gene ephrin A4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1387 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1388 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1389 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1805 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1390 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1391 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:155058284-155058452 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1392 Neighboring gene ephrin A3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:155065994-155066608 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:155075818-155075984 Neighboring gene Sharpr-MPRA regulatory region 6409 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1393 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1806 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1394 Neighboring gene ephrin A1 Neighboring gene solute carrier family 50 member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_092308.1 

    Range
    101..940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    155125731..155126570
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    154265079..154265918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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