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LOC127272535 H3K4me1 hESC enhancer GRCh37_chr2:10205669-10206546 [ Homo sapiens (human) ]

Gene ID: 127272535, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127272535
Gene description
H3K4me1 hESC enhancer GRCh37_chr2:10205669-10206546
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272535 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (10065542..10066419)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (10094285..10095162)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (10205669..10206546)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene KLF11 promoter region Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11151 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11152 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11153 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10185594-10186333 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10188595-10189095 Neighboring gene KLF11 divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:10197717-10198660 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:10198661-10199603 Neighboring gene KLF transcription factor 11 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10200462-10201324 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10201325-10202185 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10203342-10203940 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10203941-10204538 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10204790-10205668 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10211417-10211918 Neighboring gene cystin 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11154 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11155 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11156 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11157 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15296 Neighboring gene uncharacterized LOC124900536 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:10231300-10231817 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15297 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:10259653-10260596 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:10260597-10261539 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:10261588-10262143 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:10262327-10262827 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr2:10273128-10273791 Neighboring gene ribonucleotide reductase regulatory subunit M2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11159 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:10282796-10283457 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094386.1 

    Range
    101..978
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    10065542..10066419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    10094285..10095162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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