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LOC127272968 H3K4me1 hESC enhancer GRCh37_chr2:28583785-28584472 [ Homo sapiens (human) ]

Gene ID: 127272968, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127272968
Gene description
H3K4me1 hESC enhancer GRCh37_chr2:28583785-28584472
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272968 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (28360918..28361605)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (28404201..28404888)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (28583785..28584472)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene BRISC and BRCA1 A complex member 2 Neighboring gene uncharacterized LOC100505716 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:28532030-28533229 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:28542037-28543032 Neighboring gene ribosomal protein L23a pseudogene 34 Neighboring gene MPRA-validated peak3639 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:28562837-28563456 Neighboring gene uncharacterized LOC105374381 Neighboring gene uncharacterized LOC105374382 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:28582187-28583386 Neighboring gene uncharacterized LOC105374383 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28602778-28603278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28603279-28603779 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11307 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:28615755-28616686 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28616842-28617342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28617343-28617843 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15515 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28635908-28636512 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:28636513-28637117 Neighboring gene FOSL2 antisense RNA 1 Neighboring gene FOS like 2, AP-1 transcription factor subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094819.1 

    Range
    101..788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    28360918..28361605
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    28404201..28404888
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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