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LOC127396798 H3K27ac hESC enhancer GRCh37_chr3:14435811-14436550 [ Homo sapiens (human) ]

Gene ID: 127396798, updated on 12-Sep-2024

Summary

Gene symbol
LOC127396798
Gene description
H3K27ac hESC enhancer GRCh37_chr3:14435811-14436550
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

See LOC127396798 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (14394311..14395050)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (14396265..14397003)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (14435811..14436550)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376958 Neighboring gene CRISPRi-validated cis-regulatory element chr3.770 Neighboring gene CRISPRi-validated cis-regulatory element chr3.771 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr3:14293769-14294968 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14308196-14308835 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14313268-14314040 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:14314041-14314814 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14314815-14315586 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14317906-14318677 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14323255-14323756 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14324521-14325022 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:14332587-14333288 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:14333289-14333989 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:14334913-14335413 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14339415-14339967 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14348760-14349494 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19503 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14364440-14365033 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_64938 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:14370566-14370759 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14373654-14374183 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_64943 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14394065-14394622 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14395183-14395740 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14395741-14396298 Neighboring gene long intergenic non-protein coding RNA 1267 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14408879-14409397 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14417978-14418496 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14418497-14419013 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14424454-14424979 Neighboring gene uncharacterized LOC105376959 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19506 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19505 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14093 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19507 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19508 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:14447712-14447882 Neighboring gene RNA, 5S ribosomal pseudogene 124 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:14451820-14453019 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14462886-14463709 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14463710-14464532 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:14469801-14469955 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14473371-14474282 Neighboring gene solute carrier family 6 member 6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14476107-14477018 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14477019-14477930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14480905-14481405 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14492974-14493781 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:14500879-14501379 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14501865-14502386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14502387-14502908 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14502909-14503430 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14513531-14514422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14537432-14537994 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14539103-14539603 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14546947-14547448 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14547449-14547948 Neighboring gene Sharpr-MPRA regulatory region 227/3570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14555415-14555916 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14559661-14560465 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:14562934-14563775 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14563776-14564616 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14566631-14567132 Neighboring gene glutamate receptor interacting protein 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:14567133-14567632 Neighboring gene RNA, U6 small nuclear 905, pseudogene

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_098768.1 

    Range
    101..840
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    14394311..14395050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    14396265..14397003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)